Encyclopedia of Signaling Molecules

2018 Edition
| Editors: Sangdun Choi

Toll-Like Receptor Adaptor Protein Family Members

  • Enda Shevlin
  • Sinéad M. MigginEmail author
Reference work entry
DOI: https://doi.org/10.1007/978-3-319-67199-4_608


Historical Background

Toll-like receptors (TLRs) play a critical role in innate immunity by providing a frontline defense mechanism against invading pathogens such as bacteria, fungi and viruses. They accomplish this by recognising evolutionarily conserved pathogen-associated molecular patterns (PAMPs) which are...

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Copyright information

© Springer International Publishing AG 2018

Authors and Affiliations

  1. 1.Department of Biology, Institute of ImmunologyNational University of Ireland MaynoothMaynoothIreland