Thymic Neuroendocrine Carcinoma
Carcinoid; Current rubrics for primary neuroendocrine tumors of the thymus include neuroendocrine carcinoma (NEC); Thymic neuroendocrine tumor
For this entry, the terminology of neuroendocrine carcinoma (NEC) will be adopted.
Mediastinal NECs are supposed to arise from thymic neuroendocrine cells of neural crest origin. They have to be distinguished from otherwise typical thymic carcinomas, which may contain scattered neuroendocrine cells, and from non-epithelial neurogenic tumors, such as paragangliomas.
Comparison of NEC classification
References and Further Reading
- Marchevsky AM, & Wick RM (2014) Neuroendocrine carcinomas of the thymus. In Pathology of the mediastinum (pp. 131–145). Cambridge University Press, Cambridge (UK).Google Scholar
- Travis WD et al. (2004) Tumors of the thymus. In Pathology and genetics of tumors of the lung, pleura, thymus and heart (pp. 145–247). IARC Press, Lyon (FR).Google Scholar