Pathology of the Pleura and Mediastinum

2018 Edition
| Editors: Timothy Craig Allen, Saul Suster

Granulomatous Pleuritis

  • Donald GuineeJr.
Reference work entry
DOI: https://doi.org/10.1007/978-3-319-66796-6_362

Synonyms

Pleural sarcoidosis; Pleural tuberculosis; Pleurisy

Definition

Granulomatous pleuritis is a descriptive term referring to granulomatous inflammation of the pleura. Causes of granulomatous pleuritis include infectious and noninfectious etiologies. Tuberculosis is the most common infectious cause. However, infection from nontuberculous mycobacteria, fungi, (e.g., Cryptococcus neoformans), parasites, and other bacteria (e.g., actinomyces) may also cause this pattern of injury. Causes of noninfectious granulomatous pleuritis include sarcoidosis, rheumatoid nodules in rheumatoid arthritis, and iatrogenic, causes among others.

Tuberculosis

Clinical Features

  • Incidence

    Worldwide, tuberculous pleuritis is the most common etiology of granulomatous pleuritis. Pleural tuberculosis is the second most common type of extrapulmonary tuberculosis (after tuberculous lymphadenitis). It accounts for 4% of tuberculosis cases in the United States and greater than 10% of cases in Spain (Baumann et...

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Authors and Affiliations

  1. 1.Department of Pathology, C6-PTHVirginia Mason Medical CenterSeattleUSA