Pathology of the Pleura and Mediastinum

2018 Edition
| Editors: Timothy Craig Allen, Saul Suster

Collagen Vascular Disease, Pleural

  • Elizabeth McQuitty
  • Timothy Craig Allen
Reference work entry
DOI: https://doi.org/10.1007/978-3-319-66796-6_351

Synonyms

Connective tissue disorders; Lupus effusion; Lupus pleuritis; Rheumatic pleuritis

Definition

Collagen vascular diseases are a complex group of systemic inflammatory diseases generally considered autoimmune in etiology. Current data supports that these result from the interplay of genetic factors, autoantibodies, immune complexes, hormones, and other factors.

This disease group includes systemic lupus erythematosus (hyperlink), rheumatoid arthritis (hyperlink), progressive systemic sclerosis (hyperlink), polymyositis/dermatomyositis (hyperlink), Sjögren syndrome (hyperlink), overlap syndromes such as mixed connective tissue disease (hyperlink), undifferentiated connective tissue disease, and others.

Many collagen vascular diseases involve pulmonary parenchyma with resulting significant morbidity (hyperlink). They also involve the pleura, manifesting as pleuritis with or without pleural effusion. Pleural involvement by these diseases is variable in severity, and its onset may...

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References and Further Reading

  1. Gaubitz, M. (2008). Epidemiology of connective tissue disorders. Rheumatology, 47, 234–235.Google Scholar
  2. Gomez Carrera, L., & Bonilla Hernan, G. (2013). Pulmonary manifestations of collagen diseases. Archivos de Bronconeumología, 49, 249–260.  https://doi.org/10.1016/j.arbres.2012.11.005.CrossRefGoogle Scholar
  3. Schneider, F., Gruden, J., Tazelaar, H. D., & Leslie, K. O. (2012). Pleuropulmonary pathology in patients with rheumatic disease. Archives of Pathology and Laboratory Medicine, 136, 1242–1252.CrossRefPubMedGoogle Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.University of Texas Medical BranchHoustonUSA
  2. 2.Department of PathologyThe University of Mississippi Medical School, The University of Mississippi Medical CenterJacksonUSA