Polymorphous low-grade adenocarcinoma
Polymorphous carcinoma is a very rare breast carcinoma with epithelial cell differentiation showing morphological features similar to those referred as polymorphous low-grade adenocarcinoma in salivary glands.
Five cases of this special type of primary breast carcinoma have been reported in literature with morphological description.
Median age at presentation is 55 years, ranging from 37 to 74 years.
All the patients reported in literature are female.
Breast without the prevalence of a specific mammary quadrant.
Wide excision with axillary lymph node dissection is the choice of treatment of the cases reported in the literature, followed by radiotherapy in two patients. Although no lymph node metastases are found, polymorphous carcinoma seems to be an aggressive neoplasm and recommended treatment consists of wide excision with sentinel node biopsy and eventually axillary lymph...