Encyclopedia of Clinical Neuropsychology

2018 Edition
| Editors: Jeffrey S. Kreutzer, John DeLuca, Bruce Caplan


  • Efrain Antonio GonzalezEmail author
Reference work entry
DOI: https://doi.org/10.1007/978-3-319-57111-9_9269

Generic Name


Brand Name



Antidepressants, SSRI/%HT-1A partial agonists

Proposed Mechanism(s) of Action

Selective serotonin reuptake inhibitor and 5-HT1A receptor partial agonist.


Major depressive disorder

Off-Label Use

No common off-label use

Side Effects


Mania, suicidal ideation, suicide attempt.


Diarrhea, nausea, dizziness, xerostomia, vomiting, insomnia.

References and Readings

  1. Physicians’ desk reference (71st ed.) (2017). Montvale: Thomson PDR.Google Scholar
  2. Stahl, S. M. (2007). Essential psychopharmacology: the prescriber’s guide (2nd ed.). New York: Cambridge University Press.Google Scholar

Additional Information

  1. Free Drug Online. www.medscape.com
  2. Free Drug Online: Free Drug Online and PDA Software. www.epocrates.com
  3. Rickels, K., Athanasiou, M., Robinson, D. S., Gibertini, M., Whalen, H., & Reed, C. R. (2009). Evidence for efficacy and tolerability of vilazodone in the treatment of major depressive disorder: A randomized, double-blind, placebo-controlled trial. The Journal of Clinical Psychiatry, 70(3), 326–333. Epub 10 Mar 2009.PubMedCrossRefPubMedCentralGoogle Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.College of PsychologyNova Southeastern UniversityFort LauderdaleUSA
  2. 2.Utah State UniversityLoganUSA