Landmark Clinical, Scientific, and Professional Contributions
Investigations of Henry Molaison’s (HM) neurocognitive functioning following his surgical intervention have revolutionized our understanding of learning and memory processes. HM’s specific surgical intervention and associated cognitive impairments provided information not only about differential memory activities but also about the neural substrates involved in the mediation of these processes. Investigations of the alterations in HM’s memory led to a landmark paper by Brenda Milner, a psychologist working with HM, and William Scoville, his neurosurgeon. The paper, entitled Loss of recent memory after bilateral hippocampal lesions, was published in the Journal of Neurology, Neurosurgery, and Psychiatry in 1957; it brought about a sea change in the understanding of the neural substrates of memory. This paper has been cited more than 1800 times since its initial publication.
In this landmark paper, as well as in many others...
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References and Readings
Corkin, S. (2002). Whats new with amnesic patient H.M.? Nature Reviews Neuroscience, 3, 153–160.
Ogden, J. A. (2005). Fractured minds. New York: Oxford University Press.
Scoville, W. B. (1968). Amnesia after bilateral mesial temporal-lobe excision: Introduction to case H.M. Neuropsychologica, 6, 211–213.
Scoville, W. B., & Milner, B. (1957). Loss of recent memory after bilateral hippocampal lesions. Journal of Neurology, Neurosurgery, and Psychiatry, 20, 11–21.
Scoville, W. B., & Milner, B. (2000). Loss of recent memory after bilateral hippocampal lesions. Journal of Neuropsychiatry and Clinical Neuroscience, 12(1), 103–113.
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Alderson, A. (2018). H.M.; Also the Case of H.M., Molaison, Henry (1926–2008). In: Kreutzer, J.S., DeLuca, J., Caplan, B. (eds) Encyclopedia of Clinical Neuropsychology. Springer, Cham. https://doi.org/10.1007/978-3-319-57111-9_622
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DOI: https://doi.org/10.1007/978-3-319-57111-9_622
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