Chronic Fatigue Syndrome
Chronic fatigue immune deficiency syndrome (CFIDS); Medically unexplained symptoms (MUS); Myalgic Encephomyelitis (ME); Post-infectious fatigue syndrome (PFIS); Myalgic Encephomyelitis/Chronic Fatigue Syndrome (ME/CFS); Systemic Exertion Intolerance Disease (SEID). Nomenclature used by patients or healthcare providers is generally based on their etiologic perspective.
Short Description or Definition
Chronic fatigue syndrome is a complex illness defined by unexplained disabling fatigue and a combination of nonspecific accompanying symptoms that can have sudden or gradual onset. The diagnosis of the condition was initially defined by the Centers for Disease Control (CDC) study group (Holmes et al. 1988); they named the condition chronic fatigue syndrome (CFS). In subsequent years, case definitions for CFS were created in Australia, Great Britain (Sharpe et al. 1991; Wessely 1995), and Canada (Carruthers et al. 2003), and a pediatric case definition for ME/CFS was published in...
References and Readings
- Carruthers, B. M., Jain, A. K., De Meirleir, K. L., Peterson, D. L., Klimas, N. G., Lerner, A. M., et al. (2003). Myalgic encephalomyelitis/chronic fatigue syndrome: Clinical working case definition, Diagnostic and treatment protocols. Journal of Chronic Fatigue Syndrome, 11, 7–115.CrossRefGoogle Scholar
- DeLuca, J. (2008). Fatigue as a window to the brain. London: MIT Press.Google Scholar
- IOM Report. (2015). Review of the evidence on major ME/CFS symptoms and manifestations. In Beyond myalgic encephalomyelitis/chronic fatigue syndrome: Redefining an illness. Washington, DC: National Academy Press.Google Scholar