Encyclopedia of Clinical Neuropsychology

2018 Edition
| Editors: Jeffrey S. Kreutzer, John DeLuca, Bruce Caplan

Chronic Fatigue Syndrome

  • Gudrun LangeEmail author
Reference work entry
DOI: https://doi.org/10.1007/978-3-319-57111-9_544


Chronic fatigue immune deficiency syndrome (CFIDS); Medically unexplained symptoms (MUS); Myalgic Encephomyelitis (ME); Post-infectious fatigue syndrome (PFIS); Myalgic Encephomyelitis/Chronic Fatigue Syndrome (ME/CFS); Systemic Exertion Intolerance Disease (SEID). Nomenclature used by patients or healthcare providers is generally based on their etiologic perspective.

Short Description or Definition

Chronic fatigue syndrome is a complex illness defined by unexplained disabling fatigue and a combination of nonspecific accompanying symptoms that can have sudden or gradual onset. The diagnosis of the condition was initially defined by the Centers for Disease Control (CDC) study group (Holmes et al. 1988); they named the condition chronic fatigue syndrome (CFS). In subsequent years, case definitions for CFS were created in Australia, Great Britain (Sharpe et al. 1991; Wessely 1995), and Canada (Carruthers et al. 2003), and a pediatric case definition for ME/CFS was published in...

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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Pain and Fatigue Study CenterNew YorkUSA
  2. 2.Mount Sinai Beth Israel Medical CenterNew YorkUSA