Gamma knife is one of the most widely used stereotactic radiosurgery (SRS) devices. A concentrated dose of photon radiation is used to deliver the effect. Indications for gamma knife stereotactic radiosurgery include metastatic brain tumors, malignant gliomas, benign brain tumors, acoustic neuromas, arteriovenous malformations, and trigeminal neuralgia.
In metastatic disease of the brain, this procedure is most effective in patients with one to three brain tumors, but it is also suitable for individuals with multiple lesions. Good performance status, controlled primary disease, and lower total treated tumor volume have been found to be significant predictors for survival among patients with two or more brain lesions. The data suggest that SRS can be used and whole brain radiation therapy can be avoided in selected patients without loss of survival advantage.
Approximately, 95% of benign tumors may be controlled with this procedure.
In the management of...