Encyclopedia of Clinical Neuropsychology

2018 Edition
| Editors: Jeffrey S. Kreutzer, John DeLuca, Bruce Caplan


  • Ekaterina DobryakovaEmail author
  • Seema Shroff
Reference work entry
DOI: https://doi.org/10.1007/978-3-319-57111-9_355


The “putamen” (botanical term for the stony core of a fruit like the peach) is a nucleus located deep within the brain, forming a part of the basal ganglia.


Striatum/neostriatum = caudate nucleus (nucleus caudatus) + putamen

Lentiform nucleus = putamen + globus pallidus

Corpus striatum (dorsal division) = caudate nucleus + putamen + globus pallidus

Current Knowledge


The putamen surrounds the globus pallidus superolaterally. Anatomically, along with the globus pallidus, it forms the lentiform nucleus. Functionally, along with the caudate nucleus, it belongs to the neostriatum. Thin bundles of axons called Wilson’s pencils course the putamen as if radiating from the globus pallidus, giving it a striated appearance. The putamen is nourished by lenticulostriate arteries (penetrating branches of anterior and middle cerebral arteries).


Lateral – external capsule, claustrum, extreme capsule, insular cortex.

Medial – a sheet of myelinated nerve fibers...

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References and Readings

  1. Barr, M., & Kiernan, J. (1983). The human nervous system – An anatomical viewpoint (4th ed.). Philadelphia: Harper & Row.Google Scholar
  2. Delgado, M. R., Nystrom, L. E., Fissell, C., Noll, D. C., & Fiez, J. A. (2000). Tracking the hemodynamic responses to reward and punishment in the striatum. Journal of Neurophysiology, 84, 3072–3077.CrossRefPubMedPubMedCentralGoogle Scholar
  3. Gray’s Anatomy. (1995). (38th ed.). Pearson Professional Limited. Henry Gray: USA.Google Scholar
  4. McKim, T. H., Shnitko, T. A., Robinson, D. L., & Boettiger, C. A. (2016). Translational research on habit and alcohol. Current Addiction Reports, 3(1), 37–49.  https://doi.org/10.1007/s40429-016-0089-8.CrossRefPubMedCentralPubMedGoogle Scholar
  5. Natsheh, J. Y., & Shiflett, M. W. (2015). The effects of methylphenidate on goal-directed behavior in a rat model of ADHD. Frontiers in Behavioral Neuroscience, 9, 326.  https://doi.org/10.3389/fnbeh.2015.00326.CrossRefPubMedCentralPubMedGoogle Scholar
  6. Seger, C. A. (2008). How do the basal ganglia contribute to categorization? Their roles in generalization, response selection, and learning via feedback. Neuroscience and Biobehavioral Reviews, 32(2), 265–278.  https://doi.org/10.1016/j.neubiorev.2007.07.010.CrossRefPubMedPubMedCentralGoogle Scholar
  7. Tricomi, E., Balleine, B. W., & O’Doherty, J. P. (2009). A specific role for posterior dorsolateral striatum in human habit learning. The European Journal of Neuroscience, 29(11), 2225–2232.  https://doi.org/10.1111/j.1460-9568.2009.06796.x.CrossRefPubMedCentralPubMedGoogle Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Traumatic Brain Injury Research, Kessler FoundationWest OrangeUSA
  2. 2.Department of Anatomy and NeurobiologyVirginia Commonwealth UniversityRichmondUSA