Amyotrophic Lateral Sclerosis Functional Rating Scale
The Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS) is a validated instrument designed to assess the functional status and the disease progression in patients with amyotrophic lateral sclerosis (ALS). It is a tool that can be used to monitor functional change in a patient over time. The ALSFRS is a ten-item functional inventory which was devised for use in therapeutic trials in ALS. Each item is rated on a 0–4 scale, (with 0 being severely impaired and 4 being normal) by the patient and/or caregiver, yielding a maximum score of 40 points. The ALSFRS assesses the patients’ levels of self-sufficiency in areas of self-feeding, grooming, ambulation, and communication and swallowing. Versions are available in Spanish, Dutch, and German.
The ALSFRS was developed because clinimetric scales being utilized at the time were contaminated with impairment measurements, did not measure the broad range of disabilities that...
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