Encyclopedia of Clinical Neuropsychology

2018 Edition
| Editors: Jeffrey S. Kreutzer, John DeLuca, Bruce Caplan

Trifluoperazine

  • John C. Courtney
  • Efrain Antonio GonzalezEmail author
Reference work entry
DOI: https://doi.org/10.1007/978-3-319-57111-9_1719

Generic Name

Trifluoperazine.

Brand Name

Stelazine.

Class

Conventional Antipsychotic.

Proposed Mechanism(s) of Action

Blocks Dopamine-2 receptors.

Indication

Schizophrenia, nonpsychotic anxiety.

Off-Label Use

Other psychotic disorders, bipolar mood disorder.

Side Effects

Serious

Rare neuroleptic malignant syndrome, agranulocytosis, seizures, and increased cardiovascular risks in elderly adults.

Common

Dry mouth, constipation, blurred vision, decreased perspiration, decreased libido, hypotension, extrapyramidal symptoms, Parkinsonism, tardive dyskinesia, and hyperprolactinemia.

References and Readings

  1. Physicians’ desk reference (71st ed.) (2017). Montvale: Thomson PDR.Google Scholar
  2. Stahl, S. M. (2007). Essential psychopharmacology: The prescriber’s guide (2nd ed.). New York: Cambridge University Press.Google Scholar

Additional Information

  1. Free Drug Online and PDA Software. www.epocrates.com.

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Socorro Mental HealthPresbyterian Medical ServicesSocorroUSA
  2. 2.College of PsychologyNova Southeastern UniversityFort LauderdaleUSA
  3. 3.Utah State UniversityLoganUSA