Encyclopedia of Clinical Neuropsychology

2018 Edition
| Editors: Jeffrey S. Kreutzer, John DeLuca, Bruce Caplan

Thiothixene

  • John C. CourtneyEmail author
Reference work entry
DOI: https://doi.org/10.1007/978-3-319-57111-9_1713

Generic Name

Thiothixene

Brand Name

Navane

Class

Conventional antipsychotic

Proposed Mechanism(s) of Action

Blocks dopamine 2 receptors

Indication

Schizophrenia

Off-Label Use

Other psychotic disorders, bipolar mood disorder

Side Effects

Serious

Neuroleptic malignant syndrome, seizures, rare hepatic and/or renal toxicity; risk of death via cerebrovascular accidents in elderly patients with dementia-related psychosis

Common

Akathisia, hyperprolactinemia, amenorrhea, fatigue, weight gain, dry mouth, constipation, blurry vision, and rare lenticular pigmentation

References and Readings

  1. Physicians’ Desk Reference (62nd ed.). (2007). Montvale: Thomson PDR.Google Scholar
  2. Stahl, S. M. (2007). Essential psychopharmacology: The prescriber's guide (2nd ed.). New York: Cambridge University Press.Google Scholar

Additional Information

  1. Free drug online and PDA software: www.epocrates.com

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Socorro Mental HealthPresbyterian Medical ServicesSocorroUSA