Encyclopedia of Clinical Neuropsychology

2018 Edition
| Editors: Jeffrey S. Kreutzer, John DeLuca, Bruce Caplan

Mirtazapine

  • John C. Courtney
  • Efrain Antonio GonzalezEmail author
Reference work entry
DOI: https://doi.org/10.1007/978-3-319-57111-9_1677

Generic Name

Mirtazapine

Brand Name

Remeron and Remeron Soltab

Class

Antidepressant

Proposed Mechanism(s) of Action

Alpha 2 antagonist (presynaptic autoreceptor antagonist), 5HT2a/c and 5HT3 antagonist, and antihistamine

Indication

Major depressive disorder

Off-Label Use

Panic disorder, generalized anxiety disorder, PTSD, and sedation

Side Effects

Somnolence, weight gain, xerostomia, increased appetite, and constipation

Serious

Seizures (rare), induction of mania (rare), and agranulocytosis (rare) activation of suicidal ideation (controversial)

Common

Dry mouth, constipation, increased appetite, weight gain, sedation, dizziness, abnormal dreams, and hypotension

References and Readings

  1. Physicians’ desk reference (62nd ed.) (2007). Montvale: Thomson PDR.Google Scholar
  2. Physicians’ desk reference (71st ed.) (2017). Montvale, NJ: Thomson PDR.Google Scholar

Additional Information

  1. Free Drug Online and PDA Software. www.epocrates.com

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Socorro Mental HealthPresbyterian Medical ServicesSocorroUSA
  2. 2.College of PsychologyNova Southeastern UniversityFort LauderdaleUSA
  3. 3.Utah State UniversityLoganUSA