Encyclopedia of Clinical Neuropsychology

2018 Edition
| Editors: Jeffrey S. Kreutzer, John DeLuca, Bruce Caplan

Midazolam

  • John C. Courtney
  • Cristy Akins
  • Efrain Antonio GonzalezEmail author
Reference work entry
DOI: https://doi.org/10.1007/978-3-319-57111-9_1676

Generic Name

Midazolam

Brand Name

Versed

Class

Anxiolytic/sedative

Proposed Mechanism(s) of Action

Increases inhibitory effects of GABA and acts on benzodiazepine receptors at GABA-A chloride channel

Indication

Sedation, preoperative anxiolytic, and drug-induced amnesia

Off-Label Use

Rapid de-escalating agent for agitation

Side Effects

Apnea, drowsiness, seizure-like activity, nausea/vomiting, and cough

Serious

Respiratory depression, respiratory arrest, apnea, and cardiac arrest

Common

Hypotension, nausea, vomiting, oversedation, impaired memory, agitation, and headache

References and Readings

  1. Physicians’ desk reference (71st ed.) (2017). Montvale, NJ: Thomson PDR.Google Scholar
  2. Stahl, S. M. (2007). Essential psychopharmacology: The prescriber’s guide (2nd ed.). New York: Cambridge University Press.Google Scholar

Additional Information

  1. Free Drug Online and PDA Software. www.epocrates.com

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • John C. Courtney
    • 1
  • Cristy Akins
    • 2
  • Efrain Antonio Gonzalez
    • 3
    • 4
    Email author
  1. 1.Socorro Mental HealthPresbyterian Medical ServicesSocorroUSA
  2. 2.Mercy Family CenterMetarieUSA
  3. 3.College of PsychologyNova Southeastern UniversityFort LauderdaleUSA
  4. 4.Utah State UniversityLoganUSA