Encyclopedia of Clinical Neuropsychology

2018 Edition
| Editors: Jeffrey S. Kreutzer, John DeLuca, Bruce Caplan


  • John C. Courtney
  • Efrain Antonio GonzalezEmail author
Reference work entry
DOI: https://doi.org/10.1007/978-3-319-57111-9_1675

Generic Name


Brand Name

Ritalin, Concerta, Metadate, Daytrana



Proposed Mechanism(s) of Action

Dopamine transport antagonist


Attention deficit hyperactivity disorder and narcolepsy

Off-Label Use

Treatment resistant depression

Side Effects

Headache, hypertension, nausea, nervousness, tachycardia, angina, cardiac arrhythmia, anxiety, anger, and agitation


Psychotic episodes (particularly with IV abuse), seizures, tachycardia, hypertension, rare neuroleptic malignant syndrome, activation of manic episodes, and sudden cardiac death with those with preexisting neurocardiogenic defects


Insomnia, headache, nervousness, irritability, overstimulation, tremor, dizziness, anorexia, nausea, abdominal pain, weight loss, and blurred vision

References and Readings

  1. Physicians’ desk reference (71st ed.). (2017). Montvale, NJ: Thomson PDR.Google Scholar
  2. Stahl, S. M. (2007). Essential psychopharmacology: The prescriber’s guide (2nd ed.). New York: Cambridge University Press.Google Scholar

Additional Information

  1. Free drug online and PDA software. www.epocrates.com

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Socorro Mental HealthPresbyterian Medical ServicesSocorroUSA
  2. 2.College of PsychologyNova Southeastern UniversityFort LauderdaleUSA
  3. 3.Utah State UniversityLoganUSA