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Galantamine

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Generic Name

Galantamine

Brand Name

Nivalin, Razadyne, Razadyne ER, and Reminyl

Class

Acetylcholinesterase inhibitors, central; allosteric nicotinic/cholinergic modulator

Proposed Mechanism(s) of Action

Reversibly and competitively inhibits acetylcholinesterase, thus increasing the bioavailability of acetylcholine

Indication

Alzheimer’s disease

Off-Label Use

Memory disturbances and mild cognitive impairment

Side Effects

Serious

Seizure and syncope (both rare)

Common

Nausea, diarrhea, vomiting, anorexia, increased gastric secretion, weight loss, headache, dizziness, fatigue, and depression

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References and Readings

  • Physicians’ desk reference (71st ed.) (2017). Montvale: Thomson PDR.

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  • Stahl, S. M. (2007). Essential psychopharmacology: The prescriber’s guide (2nd ed.). New York: Cambridge University Press.

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Correspondence to Efrain Antonio Gonzalez .

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© 2018 Springer International Publishing AG, part of Springer Nature

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Courtney, J.C., Gonzalez, E.A. (2018). Galantamine. In: Kreutzer, J.S., DeLuca, J., Caplan, B. (eds) Encyclopedia of Clinical Neuropsychology. Springer, Cham. https://doi.org/10.1007/978-3-319-57111-9_1659

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