Encyclopedia of Clinical Neuropsychology

2018 Edition
| Editors: Jeffrey S. Kreutzer, John DeLuca, Bruce Caplan


  • John C. Courtney
  • Efrain Antonio GonzalezEmail author
Reference work entry
DOI: https://doi.org/10.1007/978-3-319-57111-9_1659

Generic Name


Brand Name

Nivalin, Razadyne, Razadyne ER, and Reminyl


Acetylcholinesterase inhibitors, central; allosteric nicotinic/cholinergic modulator

Proposed Mechanism(s) of Action

Reversibly and competitively inhibits acetylcholinesterase, thus increasing the bioavailability of acetylcholine


Alzheimer’s disease

Off-Label Use

Memory disturbances and mild cognitive impairment

Side Effects


Seizure and syncope (both rare)


Nausea, diarrhea, vomiting, anorexia, increased gastric secretion, weight loss, headache, dizziness, fatigue, and depression

References and Readings

  1. Physicians’ desk reference (71st ed.) (2017). Montvale: Thomson PDR.Google Scholar
  2. Stahl, S. M. (2007). Essential psychopharmacology: The prescriber’s guide (2nd ed.). New York: Cambridge University Press.Google Scholar

Additional Information

  1. Free Drug Online and PDA Software. www.epocrates.com
  2. Free Drug Online and PDA Software. www.medscape.com

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Socorro Mental HealthPresbyterian Medical ServicesSocorroUSA
  2. 2.College of Psychology, Nova Southeastern UniversityFort LauderdaleUSA
  3. 3.Utah State UniversityLoganUSA