Anterior Cingulate Cortex
The anterior cingulate cortex (ACC) is a mesocortical paralimbic area located anterior to the corpus callosum and posterior to the prefrontal cortex. The ACC was once viewed as a single limbic structure, forming an important part of the “Papez” circuit, though in reality analysis of its cytoarchitecture indicates that it consists of regions with different cell types. Its cell characteristics are agranular and therefore are distinct from the cortex.
The ACC encompasses several Brodmann areas, including areas 24, 25, 32, and 33. The ACC wraps around the corpus callosum, having the appearance of a collar or belt. In fact, the term cingulum means belt in Latin. A large volume of the ventral ACC consists of Area 24, which merges with the posterior cingulate cortex (Area 23) along the posterior half of the corpus callosum. The division between the ACC and posterior cingulate is undifferentiated to a large extent, though these areas can be separated based on the...
References and Readings
- Ballentine Jr., H. T., Levey, B. A., Dagi, T. F., & Diriunas, I. B. (1977). Neurosurgical treatment in psychiatry, pain, and epilepsy. In W. H. Sweet, S. Obrador, & J. G. Martin-Rodriques (Eds.), Cingulotomy for psychiatric illness: Report of 13 years experience (pp. 333–353). Baltimore: University Park Press.Google Scholar