Encyclopedia of Clinical Neuropsychology

2018 Edition
| Editors: Jeffrey S. Kreutzer, John DeLuca, Bruce Caplan

Medial Temporal Lobe

  • Jonathan A. OlerEmail author
  • Rothem Kovner
Reference work entry
DOI: https://doi.org/10.1007/978-3-319-57111-9_1168


Hippocampal system; Limbic lobe; Mesial temporal lobe


The medial temporal lobe is an anatomical construct composed of the cerebral cortices on the mesial surface temporal lobe, as well as the subcortical gray-matter structures that lie beneath the surface of the temporal cortex. It is also a functional construct and is a term typically associated with the parahippocampal region (perirhinal, entorhinal, and parahippocampal cortices) and the hippocampal formation (CA fields, dentate gyrus, and subicular complex), a set of highly interconnected brain areas critical for the formation of long-term episodic memory (the medial temporal lobe memory system; MTLMS). While the phrase “medial temporal lobe” is most often used in reference to the mnemonic function of the hippocampus, the amygdala, a grouping of nuclei situated just in front of the hippocampus (see Fig. 1), also technically constitutes part of the medial temporal lobe (see Fig. 2). The amygdala, however, is...
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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of PsychiatryUniversity of Wisconsin-MadisonMadisonUSA