Encyclopedia of Clinical Neuropsychology

2018 Edition
| Editors: Jeffrey S. Kreutzer, John DeLuca, Bruce Caplan

Temporal Lobe Epilepsy

  • William B. BarrEmail author
  • Stella Karantzoulis
Reference work entry
DOI: https://doi.org/10.1007/978-3-319-57111-9_1058

Synonyms

Limbic epilepsy; Psychomotor epilepsy; Temporolimbic epilepsy

Definition

Temporal lobe epilepsy (TLE) is a form of partial epilepsy characterized by recurrent seizures originating from the medial or lateral temporal lobe. It is considered to be the most common (80%) of all epileptic syndromes. The etiology of TLE is often characterized as idiopathic, indicating that its cause is not related to a readily identified brain lesion. TLE is most commonly associated with complex partial seizures, although a large number of individuals with TLE also experience simple partial and/or secondary generalized tonic-clonic seizures. The syndrome of TLE has been associated with features extending well beyond the occurrence of seizures, with many patients experiencing specific forms of cognitive dysfunction and psychiatric comorbidity.

Current Knowledge

The medical literature has traditionally characterized TLE as a unitary syndrome. This trend has changed in recent years owing to numerous...

This is a preview of subscription content, log in to check access.

References and Readings

  1. Bell, B., Lin, J. J., Seidenberg, M., & Hermann, B. P. (2011). The neurobiology of cognitive disorders in temporal lobe epilepsy. Nature Reviews Neurology, 7, 154–164.CrossRefGoogle Scholar
  2. Helmstaedter, C. (2013). Cognitive outcomes of different surgical approaches in temporal lobe epilepsy. Epileptic Disorders, 15, 221–239.PubMedGoogle Scholar
  3. Jobst, B. C., & Cascino, G. D. (2015). Resective epilepsy surgery for drug-resistant focal epilepsy: A review. JAMA, 313, 285–293.CrossRefGoogle Scholar
  4. Kanner, A. M., & Hesdorfer, D. C. (2012). Neuropsychiatric complications of epilepsy. In H. Stefan. & W.H. Theodore (Eds.), Handbook of clinical neurology (Epilepsy, Part I, Vol. 107, pp. 461–482). Elsevier B.V., Amsterdam.Google Scholar
  5. Kennedy, J. D., & Scheule, S. U. (2012). Neocortical temporal lobe epilepsy. Journal of Clinical Neurophysiology, 29, 366–370.CrossRefGoogle Scholar
  6. Tatum, W. O. (2012). Mesial temporal lobe epilepsy. Journal of Clinical Neurophysiology, 29, 356–365.CrossRefGoogle Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.NYU Langone Medical CenterComprehensive Epilepsy CenterNew YorkUSA
  2. 2.Modern Brain CenterNew YorkUSA