Personalized Medicine

  • Federico Goodsaid
  • Felix Frueh
  • Michael E. Burczynski
Living reference work entry


Personalized medicine (PM) has grown in both clinical importance and in cultural recognition and popularity over the last two decades. In this chapter we will first address the different public perceptions of the term “personalized medicine,” with the ultimate goal of identifying the definition(s) of PM which best reflect how it is currently prosecuted within modern drug development. A brief historical context will then be provided, followed by a discussion of the general tenets of personalized medicine as employed within the pharmaceutical industry and in clinical practice. The chapter concludes with some tables and a small number of case studies that highlight the PM concept in both oncology and rare diseases and a consideration of what the future holds for the field.

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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Federico Goodsaid
    • 1
  • Felix Frueh
    • 1
  • Michael E. Burczynski
    • 2
  1. 1.Opus Three LLC Life SciencesPescaderoUSA
  2. 2.Department of Translational Medicine, Global R&DTeva PharmaceuticalsFrazerUSA

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