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Cutaneous Outcome Measures of Adult Dermatomyositis

  • Rebecca G. Gaffney
  • Victoria P. WerthEmail author
Living reference work entry

Abstract

Dermatomyositis is an autoimmune skin disease marked by inflammation of the skin and muscle. The skin manifestations significantly impact quality of life and are difficult to treat. Therefore, clinical trials for effective therapies to treat the skin involvement in dermatomyositis are critical. There are many validated outcome measures that allow physicians to objectively evaluate response to treatment in clinical trials and in the clinic. This chapter reviews the following popular tools to assess skin severity in dermatomyositis: the Cutaneous Dermatomyositis Disease Area and Severity Index, the Physician Global Assessment, and the Cutaneous Assessment Tool-Binary Method. Based on validation studies outlined in this chapter, it appears that the Cutaneous Dermatomyositis Disease Area and Severity Index demonstrates superiority over the other tools and is a useful outcome measure for dermatomyositis.

Keywords

Dermatomyositis Clinical trials Validated tools CDASI PGA CAT-BM 

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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Department of DermatologyCorporal Michael J. Crescenz VAMCPhiladelphiaUSA
  2. 2.Department of DermatologyUniversity of Pennsylvania, Perelman School of MedicinePhiladelphiaUSA
  3. 3.Rutgers Robert Wood Johnson Medical SchoolNew BrunswickUSA

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