Phenolic Lipids Synthesized by Type III Polyketide Synthases
Phenolic lipids, consisting of a polar aromatic ring and a hydrophobic alkyl chain, are distributed widely in bacteria, fungi, and plants, and they appear to play important roles in biological membranes. Here, recent studies of the biosynthesis of microbial and plant phenolic lipids are described. Phenolic lipids are biosynthesized by a combination of a fatty acid synthase and a type III polyketide synthase, which are responsible for synthesizing the alkyl chain and the aromatic ring, respectively.
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