Genomic imprinting is an epigenetic phenomenon which results in the monoallelic expression of a gene depending on the parental origin. Genomic imprints may be covalent (DNA methylation) or noncovalent (DNA-protein and DNA-RNA interactions, genomic localization in nuclear space) and the process of imprinting encompasses the specialized nuclear enzymatic machinery which maintains parental epigenetic marks throughout the life.
How Imprinting Works?
- Kobayashi, H., Yamada, K., Morita, S., Hiura, H., Fukuda, A., Kagami, M., … Kono, T. (2009). Identification of the mouse paternally expressed imprinted gene Zdbf2 on chromosome 1 and its imprinted human homolog ZDBF2 on chromosome 2. Genomics, 93(5), 461–472.Google Scholar