Anaplastic and Other Forms of Thyroid Carcinoma

  • Leonard WartofskyEmail author
Reference work entry
Part of the Endocrinology book series (ENDOCR)


This chapter describes the more relatively rare thyroid malignancies other than the well-differentiated thyroid cancers and medullary thyroid carcinoma that are discussed above in their specific chapters. Included in this section are the separate entities of anaplastic thyroid carcinoma, primary thyroid lymphoma, teratoma of the thyroid, squamous cell carcinoma, mucoepidermoid carcinoma, sarcoma, and the SETTLE (spindle epithelial tumor with thymus-like elements) tumor. Aspects of the epidemiology, clinical presentation, pathology, and treatment including surgery, chemotherapy, and external radiation are discussed. Most of these tumors are quite poorly differentiated, and unless diagnosed and treated aggressively early, the prognosis is bleak, because the therapeutic armamentarium is relatively limited.


Anaplastic thyroid carcinoma Primary thyroid lymphoma Teratoma of the thyroid Squamous cell carcinoma Mucoepidermoid carcinoma Sarcoma SETTLE tumor CASTLE tumor Cytology Chemotherapy External radiation 


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© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of EndocrinologyMedStar Washington Hospital Center, Georgetown University School of MedicineWashingtonUSA

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