Lung Cancer in Older Adults: Local Treatment

  • Drew Moghanaki
  • Carlos E. Bravo Iñiguez
  • Michael T. Jaklitsch
Living reference work entry


Lung cancer is a malignancy that primarily affects the elderly. It is commonly diagnosed in patients with co-morbidiies who may have concerns about complications from aggressive therapies. This chapter is written for the non-oncologist to provide guidance on how best to approach elderly patients with lung cancer. An emphasis is made regarding the value of a multi-disciplinary team-based approach, given the evidence continues to evolve for an optimal approach in many clinical situations. It descirbes the advantages of minimally invasive thoracic surgery that have been reported in randomized clinical trials. It also summarizes the serendipitous outcomes following stereotactic radiotherapy for early stage disease that currently calls into question the time-honored belief that surgery provides the only hope for cure. A section is dedicated to the evoluation of treatment paradigms for patients with locally advanced lung cancer which has led to lower doses and smaller fields of radiotherapy than ever before. Finally, an update is provided regarding management options for localized small cell lung cancer.


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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Drew Moghanaki
    • 1
  • Carlos E. Bravo Iñiguez
    • 2
  • Michael T. Jaklitsch
    • 3
  1. 1.Radiation Oncology ServiceHunter Holmes McGuire Veterans Affairs Medical CenterRichmondUSA
  2. 2.Department of Surgery, Division of Thoracic SurgeryBrigham and Women’s Hospital, Harvard Medical SchoolBostonUSA
  3. 3.Department of Surgery, Division of Thoracic SurgeryBrigham and Women’s Hospital/Dana-Farber Cancer InstituteBostonUSA

Section editors and affiliations

  • Etienne Brain
    • 1
  1. 1.Department of Medical Oncology, Institute CurieHôpital René HugueninSaint-CloudFrance

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