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Radiotherapy for Localized and Locally Advanced Prostate Cancer

  • Alberto Bossi
  • Warren R. Bacorro
  • Gabriele Coraggio
Living reference work entry

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Abstract

Radiotherapeutic management encompasses all stages of prostate cancer. Conformal and intensity-modulated techniques have made possible dose-escalated external radiotherapy improving survival outcomes in localized disease and reducing toxicity in the postoperative adjuvant setting. Stereotactic techniques, under rigorous conditions, permit moderate and extreme hypofractionation which shortens the overall treatment time. In the curative setting, this can be a tool for dose escalation by taking advantage of the radiobiologic properties of prostate cancer. In the palliative setting, this allows for shorter regimens and, more importantly, re-irradiation. Finally, with the advent of transrectal ultrasonography, prostate brachytherapy has emerged as a versatile tool, either as a monotherapy in the treatment of low- or intermediate-risk disease, as a boost to external radiotherapy in high-risk disease, or as salvage treatment.

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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Alberto Bossi
    • 1
  • Warren R. Bacorro
    • 2
    • 4
  • Gabriele Coraggio
    • 3
  1. 1.Department of Radiation Oncology, Genito Urinary UnitGustave RoussyVillejuifFrance
  2. 2.Department of Radiation OncologyGustave RoussyVillejuifFrance
  3. 3.Departement of Radiation Oncology Genitourinary UnitHenry MONDOR Hospital APHPCreteilFrance
  4. 4.Brachytherapy Unit, Department of Radiation OncologyUniversity of Santo Tomas Hospital - Benavides Cancer InstituteManilaPhilippines

Section editors and affiliations

  • Thomas Steuber
    • 1
  1. 1.Martini-Klinik am UKE GmbHHamburgGermany

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