Inflammatory Myofibroblastic Tumor, Upper Gastrointestinal Tract
Inflammatory myofibroblastoma; Inflammatory myofibrohistiocytic proliferation; Inflammatory pseudotumor; Plasma cell granuloma; Plasma cell pseudotumor
The inflammatory myofibroblastic tumor comprises spindle or polygonal fibroblast-/myofibroblast-type cells, which often express anaplastic lymphoma kinase (ALK), and stromal lymphoplasmacytic inflammatory cells. Some authors have differentiated inflammatory myofibroblastic tumors from reactive pseudosarcomatous processes and other neoplasms based on ALK immunoreactivity or evidence of the ALK translocation, but many consider ALK-negative inflammatory myofibroblastic tumors a valid diagnostic category.
Inflammatory myofibroblastic tumors (IMTs) are rare in the upper gastrointestinal (GI) tract.
Inflammatory myofibroblastic tumors mean age (range) is 41 years (0.75–84) (Makhlouf and Sobin 2002).
The male to female ratio of inflammatory myofibroblastic tumors is 1.1:1 (Makhlouf and...