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Epstein-Barr Virus (EBV), Esophagitis

  • Reference work entry
  • First Online:
Pathology of the Gastrointestinal Tract

Part of the book series: Encyclopedia of Pathology ((EP))

  • 183 Accesses

Synonyms

Human herpesvirus four esophagitis

Definition

Epstein-Barr virus (EBV) esophagitis is a form of esophagitis caused by herpesvirus in immunocompetent or immunocompromised patients.

EBV is a ubiquitous virus that infects and establishes a persistent infection in the host. Clinically, it causes two types of infection: the primary infection, which ranges from a mild self-limited illness in children to infectious mononucleosis in adolescents and adults, and the reactivation of latent infection in immunocompromised patients (Gesser 1997). EBV replicates and is shed periodically from epithelial cells in the oropharynx or from salivary glands and persists through interactions with two different host cell types: epithelial cells at the surface of the body that are fully permissive for the production of infectious virus and serve to transmit the virus from person to person and cells situated deeper in the body that generally are nonpermissive and function as a reservoir of latent virus.

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References and Further Reading

  • Gesser, R. M. (1997). The role of latency in herpesvirus infections. Seminars in Pediatric Infectious Diseases, 8(3), 128–135.

    Article  Google Scholar 

  • Gulley, M. L. (2001). Molecular diagnosis of Epstein-Barr virus-related diseases. The Journal of Molecular Diagnostics, 3(1), 1–10.

    Article  CAS  Google Scholar 

  • Kitchen, V. S., Helbert, M., Francis, N. D., Logan, R. P. H., et al. (1990). Epstein-Barr virus associated oesophageal ulcers in AIDS. Gut, 31, 1223–1225.

    Article  CAS  Google Scholar 

  • Pape, M., Mandraveli, K., Sidiropoulos, I., et al. (2009). Unusual Epstein-Barr esophageal infection in an immunocompetent patient: A case report. Journal of Medical Case Reports, 3, 7314.

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  • Pattengale, P. K., Smith, R. W., & Gerber, P. (1973). Selective transformation of B lymphocytes by EB virus. Lancet, ii, 93–94.

    Article  Google Scholar 

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Author information

Authors and Affiliations

  1. Hospital Cuf Descobertas and Escola Superior de Tecnologia da Saúde de Lisboa and Instituto de Anatomia Patológica, Faculdade de Medicina da, Universidade de Lisboa, Parque das Nações, Rua Mário Botas, 1998-018, Lisboa, Portugal

    Paula Borralho Nunes

Authors
  1. Paula Borralho Nunes
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Corresponding author

Correspondence to Paula Borralho Nunes .

Editor information

Editors and Affiliations

  1. Faculty of Medicine of Porto University, Centro Hospitalar São João and Ipatimup/i3S, Porto, Portugal

    Fátima Carneiro

  2. Serviço de Anatomia Patológica, Instituto Português de Oncologia de Lisboa de Francisco Gentil, Lisbon, Portugal

    Paula Chaves

  3. Faculdade de Ciências da Saúde, Universidade da Beira Interior, Covilhã, Portugal

    Paula Chaves

  4. Department of Pathology, Ankara University Medical School, Sihhiye, Ankara, Turkey

    Arzu Ensari

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Nunes, P.B. (2017). Epstein-Barr Virus (EBV), Esophagitis. In: Carneiro, F., Chaves, P., Ensari, A. (eds) Pathology of the Gastrointestinal Tract. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-40560-5_1589

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  • DOI: https://doi.org/10.1007/978-3-319-40560-5_1589

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-40559-9

  • Online ISBN: 978-3-319-40560-5

  • eBook Packages: MedicineReference Module Medicine

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