Pathology of the Gastrointestinal Tract

2017 Edition
| Editors: Fátima Carneiro, Paula Chaves, Arzu Ensari

Duplication, Esophagus

  • Susana Mão de FerroEmail author
  • Miguel Serrano
Reference work entry


Congenital duplications; Gastrointestinal duplication cyst


Gastrointestinal duplication (GD) is a rare congenital anomaly that arises during early embryonic development and may occur anywhere along the gastrointestinal tract, from the mouth to the anus.

The cause of GD remains unclear. The most popular theory is the abnormal recanalization hypothesis. During the sixth week of fetal development, a proliferation of epithelium completely occludes the lumen of the gut, and vacuoles develop within the occluded lumen. Vacuoles coalesce until the lumen of the gut tube is fully recanalized. Duplication may occur due to an abnormal persistence of vacuoles. Other hypotheses include persistent embryologic diverticulum, bronchopulmonary foregut malformations, or intrauterine vascular accidents.

There are two general types of GD. Cystic duplications account for approximately 80% of cases, are spherical in shape, and have no communication with the bowel lumen. Tubular...

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References and Further Reading

  1. Banner, K., Helft, S., Kadam, J., Miah, A., & Kaushik, N. (2008). An unusual cause of dysphagia in a young woman: Esophageal duplication cyst. Gastrointestinal Endoscopy, 68(4), 793.CrossRefGoogle Scholar
  2. Lee, K. N., Kim, S., Jeon, T. Y., Sung, H., Kim, H. S., Kim, D. H., Seo, H. I., Park, D. Y., Jang, H. J., et al. (2010). Complications of congenital and development abnormalities of the gastrointestinal tract in adolescents and adults: Evaluation with multimodality imaging. Radiographics, 30, 1489–1507.CrossRefGoogle Scholar
  3. Long, J., Orlando, R. Esophageal duplication. In Sleisenger and Fordtran’s gastrointestinal and liver disease (9th edn, p. 671). Saunders Elsevier.Google Scholar
  4. Olajide, A. R., Yisau, A., Abdulraseed, N., Kashim, I., Olaniyi, A., & Morohunfade, A. (2010). Gastrointestinal duplications: Experience in seven children and review of the literature. Saudi Journal of Gastroenterology, 16(2), 105–109.CrossRefGoogle Scholar
  5. Tahri, N. (2012). Complete endoscopic management of tubular esophageal duplication in a young woman. Endoscopy, 44, E261–E262.CrossRefGoogle Scholar

Copyright information

© Springer International Publishing AG 2017

Authors and Affiliations

  1. 1.Department of GastroenterologyIPOLFG, E.P.E.LisbonPortugal