Pathology of the Gastrointestinal Tract

2017 Edition
| Editors: Fátima Carneiro, Paula Chaves, Arzu Ensari

Adipose Tissue Tumors, Stomach

  • José Manuel LopesEmail author
Reference work entry


Atypical lipomatous tumor/well differentiated liposarcoma; Dedifferentiated liposarcoma; Lipoma; Myxoid liposarcoma; Pleomorphic liposarcoma


Lipoma is a benign tumor consisting of mature adipocytes.

Atypical lipomatous tumor/well-differentiated liposarcoma is an intermediate malignant tumor consisting of pleomorphic adipocytes and stromal cells with at least focal nuclear atypia.

Dedifferentiated liposarcoma: tumor displaying transition from atypical lipomatous tumor/well-differentiated liposarcoma to other non-adipocytic type mesenchymal tumor with variable malignant grade (sarcoma).

Myxoid liposarcoma is a sarcoma containing variable number of signet-ring lipoblasts and round/oval mesenchymal primitive cells surrounded by a myxoid stroma with delicate arborizing vessels.

Pleomorphic liposarcoma: high-grade sarcoma consisting of variable number of pleomorphic lipoblasts in the absence of atypical lipomatous tumor/well-differentiated liposarcoma features.


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References and Further Reading

  1. Krasniqi, A. S., Hoxha, F. T., Bicaj, B. X., Hashani, I. A., Hasimja, S. M., Kelmendi, S. M., & Gashi-Luci, L. H. (2008). Symptomatic subserosal gastric lipoma successfully treated with enucleation. World Journal of Gastroenterology, 14, 5930–5932.PubMedPubMedCentralGoogle Scholar
  2. Kuhnen, C., Mentzel, T., Haarmann, W., Schwegler, U., Sciot, R., Debiec-Rychter, M., et al. (2010). Atypical lipomatous tumors of the stomach. Clinical, morphological and molecular findings. Pathologe, 31, 199.PubMedGoogle Scholar
  3. Seki, K., Hasegawa, T., Konegawa, R., Hizawa, K., & Sano, T. (1998). Primary liposarcorma of the stomach: A case report and a review of the literature. Japanese Journal of Clinical Oncology, 28, 284–288.PubMedGoogle Scholar
  4. Thompson, W. M., Kende, A. I., & Levy, A. D. (2003). Imaging characteristics of gastric lipomas in 16 adult and pediatric patients. American Journal of Radiology, 181, 981–985.Google Scholar

Copyright information

© Springer International Publishing AG 2017

Authors and Affiliations

  1. 1.Faculty of Medicine of the University of Porto and Institute of Molecular Pathology and Immunology of the University of PortoPortoPortugal