Pathology of the Gastrointestinal Tract

2017 Edition
| Editors: Fátima Carneiro, Paula Chaves, Arzu Ensari

Mucocele, Appendix

  • Magali Svrcek
Reference work entry
DOI: https://doi.org/10.1007/978-3-319-40560-5_1514

Synonyms

Appendiceal mucinous cystadenoma; Low-grade appendiceal mucinous neoplasm (LAMN); Low-grade appendiceal mucinous tumor; Mucosal hyperplasia; Retention cyst; Retention mucocele

Definition

Appendiceal mucocele is an obstructive dilatation of the appendix caused by intraluminal accumulation of mucoid material (Fig. 1a, b). This purely descriptive term was first coined by Rokitansky in 1855, and does not constitute a pathological diagnosis. The density of goblet cells is far greater within the epithelium of the appendix than within the colon. As a result, the most frequent appendiceal epithelial tumors are mucinous and begin as mucoceles.
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References and Further Reading

  1. Carr, N. J., & Sobin, L. H. (2010). Tumours of the appendix. In F. T. Bosman, F. Carneiro, R. H. Hruban, & N. D. Theise (Eds.), WHO classification of tumours of the digestive system (pp. 122–125). Lyon: IARC Press.Google Scholar
  2. Carr, N. J., Finch, J., Ilesley, I. C., et al. (2012). Pathology and prognosis in pseudomyxoma peritonei: A review of 274 cases. Journal of Clinical Pathology, 65, 919–923.CrossRefPubMedGoogle Scholar
  3. Chua, T. C., Moran, B. J., Sugarbaker, P. H., et al. (2012). Early- and long-term outcome data of patients with pseudomyxoma peritone from appendiceal origin treated by a strategy of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. Journal of Clinical Oncology, 20, 2449–2456.CrossRefGoogle Scholar
  4. Higa, E., Rosai, J., & Pizzimbono, C. A. (1973). Mucosal hyperplasia, mucinous cystadenoma and mucinous cystadenocarcinoma of the appendix: A re-evaluation of appendiceal “mucocele”. Cancer, 32, 1525–1541.CrossRefPubMedGoogle Scholar
  5. Smeenk, R. M., van Velthuysen, M. L., Verwaal, V. J., & Zoetmulder, F. A. (2008). Appendiceal neoplasms and pseudomyxoma peritonei: A population-based study. European Journal of Surgical Oncology, 34, 196–201.CrossRefPubMedGoogle Scholar

Copyright information

© Springer International Publishing AG 2017

Authors and Affiliations

  1. 1.Hôpital Saint-Antoine, Service d’Anatomie PathologiqueAP-HP, Hôpitaux Universitaires de l’Est ParisienParisFrance