Intestinal atresia and stenosis
Intestinal atresia is a complete blockage of intestinal passage caused by mucosal diaphragm which totally occludes the lumen. Stenosis is formed by narrowed segment of the intestine or the mucosal diaphragm with small opening. Intestinal atresia and stenosis are responsible for most cases of bowel obstruction in newborns.
Failed recanalization of the intestine during 12-th fetal week
Retarded epithelial growth during intestinal elongation which is slower than mesenchymal growth
Vascular abnormalities in utero leading to ischemia and segmental necrosis with subsequent scaring and development of atresia
References and Further Reading
- Fenoglio-Preiser, C., et al. (1999). Gastrointestinal pathology plus: An atlas and text. Philadelphia: Lippincott Williams & Wilkins.Google Scholar
- Intestinal atresia and stenosis. www.cincinnatichildrens.org/health/i/obstructions/