Inflammatory Fibroid Polyp, Lower Gastrointestinal Tract
Eosinophilic submucosal granuloma; Vanek’s tumor
Inflammatory fibroid polyp (IFP) is a rare mesenchymal lesion of the gastrointestinal tract first described by Vanek in 1949. In 1953, Helwig and Ranier proposed the term “inflammatory fibroid polyp,” which is generally accepted at present. IFPs are most commonly found in the stomach but can occur throughout the GI tract and in one series were more prevalent in the small bowel. IFPs have been reported in different sites, such as the esophagus, duodenum, and ileoanal pouch, but they occur relatively rare in colorectum.
Presenting symptoms can vary and may include abdominal pain, weight loss, and symptoms of GI obstruction or intussusception. IFP may also present as an incidental finding on routine endoscopic examination. IFPs may be associated with concurrent neoplastic (carcinoma, adenomatous polyps) and non-neoplastic (usually inflammatory) lesions of the GI tract.
IFPs are very rare...
References and Further Reading
- Miettinen, M., Fletcher, C. D. M., Kindblom, L. -G., & Tsui, W. M. S. (2010). World Health Organization classification of tumours. Pathology & genetics. Tumours of the digestive system. In F. T. Bosman, F. Carnerio, R. H. Hruban, & N. D. Theise (Eds.), Mesencymal tumours of the small intestine (pp. 115–118). Lyon: International Agency for research on cancer (IARC).Google Scholar