Pathology of the Gastrointestinal Tract

2017 Edition
| Editors: Fátima Carneiro, Paula Chaves, Arzu Ensari

Diverticular Colitis

  • Gert De HertoghEmail author
Reference work entry


Crescentic fold disease; Diverticular disease-associated chronic colitis; Isolated sigmoiditis; Segmental colitis associated with diverticulosis (SCAD)


Diverticular colitis can be defined operationally as mucosal inflammation within a colon segment containing diverticula. It primarily affects the sigmoid colon. It is however distinct from diverticulitis, which is inflammation of one or more diverticula and the surrounding connective and muscle tissues. Diverticular colitis is noteworthy for mimicking chronic inflammatory bowel disease (IBD), both endoscopically and histologically.

Clinical Features

  • Incidence

    Only a subset of patients with diverticulosis coli also develops diverticular colitis. Estimates vary between less than 1% and 4%. The true incidence and prevalence are probably underestimated as many patients do not develop worrisome symptoms. The most common presenting complaints are cramping left lower quadrant pain or tenesmus, constipation or diarrhea which...

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References and Further Reading

  1. Burroughs, S. H., Bowrey, D. J., Morris-Stiff, G. J., et al. (1998). Granulomatous inflammation in sigmoid diverticulitis: Two diseases or one? Histopathology, 33, 349–353.CrossRefGoogle Scholar
  2. Goldstein, N. S., Leon-Armin, C., & Mani, A. (2000). Crohn’s colitis-like changes in sigmoid diverticulitis specimens is usually an idiosyncratic inflammatory response to the diverticulosis rather than Crohn’s colitis. The American Journal of Surgical Pathology, 24, 668–675.CrossRefGoogle Scholar
  3. Lamps, L. W., & Knapple, W. L. (2007). Diverticular disease-associated segmental colitis. Clinical Gastroenterology and Hepatology, 5, 27–31.CrossRefGoogle Scholar
  4. Makapugay, L. M., & Dean, P. J. (1996). Diverticular disease-associated chronic colitis. The American Journal of Surgical Pathology, 20, 94–102.CrossRefGoogle Scholar
  5. Tursi, A. (2011). Segmental colitis associated with diverticulosis: Complication of diverticular disease or autonomous entity? Digestive Diseases and Sciences, 56, 27–34.CrossRefGoogle Scholar

Copyright information

© Springer International Publishing AG 2017

Authors and Affiliations

  1. 1.Department of PathologyPathologische Ontleedkunde, UZ LeuvenLeuvenBelgium