Leather and Shoes

  • Johannes GeierEmail author
  • Holger Lessmann
Living reference work entry


  • In the production and processing of leather and in the manufacture of shoes, various allergenic and irritating substances are used.

  • Occupational skin disease is infrequently reported in these branches.

  • The most important allergens are chromium salts, p-tert-butylphenol formaldehyde resin, rubber chemicals, and various biocides.

  • Many possible allergens are not available for routine diagnostics, so sensitization may be overlooked.

  • Residuals of allergens in leather or shoes also pose a risk for the consumer.


Leather Tanning Chromium salts Cobalt Formaldehyde Glutaraldehyde Azo dyes Mercaptobenzothiazole Bismarck brown Metanil yellow Disperse orange 3 Chloroacetamide Octylisothiazolinone Dimethylfumarate 


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Authors and Affiliations

  1. 1.Information Network of Departments of Dermatology (IVDK)University Medical Center GoettingenGoettingenGermany

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