Pancreatic Solid-Pseudopapillary Neoplasm, Cytological Findings
Synonyms
Frantz tumor; Hamoudi tumor; Low grade papillary neoplasm; Papillary and solid neoplasm; Papillary-cystic neoplasm; Papillary-cystic tumor; Papillary epithelial neoplasm; Papillary-cystic carcinoma; Papillary-cystic epithelial neoplasm; Solid and cystic acinar cell tumor; Solid and cystic tumor; Solid and papillary epithelial neoplasm; Solid and papillary neoplasm; Solid-pseudopapillary tumor
Definition
Solid-pseudopapillary neoplasms (SPNs) are rare, well-circumscribed, solid, secondarily cystic epithelial neoplasms that form pseudopapillary structures. The cell of origin is unknown.
Clinical Features
Incidence
SPNs comprise 1–2% of all pancreatic exocrine tumors (Song et al. 2012).
Age
Mean age of presentation ranges from 22 to 28 years old, but they can occur in older adults (Chakhachiro and Zaatari 2009).
Sex
Ninety percent occur in young women (Chakhachiro and Zaatari 2009).
Site
SPNs show no site predilection within the pancreas (Chakhachiro and Zaatari 2009).
Treatment
S...
References and Further Reading
- Chakhachiro, Z. I., & Zaatari, G. (2009). Solid-pseudopapillary neoplasm: A pancreatic enigma. Archives of Pathology & Laboratory Medicine, 133(12), 1989–93.Google Scholar
- Hruban, R. H., Pitman, M. B., & Klimstra, D. S. (2007). Tumors of the pancreas (Atlas of tumor pathology, 4th series, fascicle 6). Washington, DC: American Reigstry of Pathology; Armed Forces Institutes of Pathology.Google Scholar
- Mortenson, M. M., Katz, M. H., Tamm, E. P., Bhutani, M. S., Wang, H., Evans, D. B., & Fleming, J. B. (2008). Current diagnosis and management of unusual pancreatic tumors. American Journal of Surgery, 196(1), 100–13. doi:10.1016/j.amjsurg.2008.02.005. Epub 2008 May 7.PubMedCrossRefGoogle Scholar
- Song, J. S., Yoo, C. W., Kwon, Y., & Hong, E. K. (2012). Endoscopic ultrasound-guided fine needle aspiration cytology diagnosis of solid pseudopapillary neoplasm: Three case reports with review of literature. Korean Journal of Pathology, 46(4), 399–406. Epub 2012 Aug 23.PubMedPubMedCentralCrossRefGoogle Scholar