Drug Delivery via Nanomachines
Drug delivery via nanomachines is one type of targeted drug delivery (TDD) technologies that delivers medicament to the designated area in vivo by using devices ranging in size from 0.1 to 10 μm and constructed of nanoscale components. Various terms such as nanomachine, nanorobot, nanobot, nanoid, nanite, and nanomite have been used to describe such devices. These nanomachines are loaded with drugs and targeted solely to diseased tissue under the manipulation and guidance of an external monitoring system. The purpose of this technology is to remarkably enhance locoregional therapies for disease treatment while reducing the side-effects of the drug on healthy cells.
In traditional drug delivery systems such as oral ingestion or intravascular injection, the medication is distributed throughout the body via the systemic blood circulation. For most therapeutic agents, only a small portion of the medication reaches the organ...
- IEEE NanoCom Standards Development Working Group (2017) IEEE recommended practice for nanoscale and molecular communication framework, IEEE standard 1906.1–2015, 2016Google Scholar
- Sagnella S, Drummond C (2012) Drug delivery: a nanomedicine approach. Aust Biochemist 43:5–8Google Scholar
- Trafton A (2009) Tumors targeted using tiny gold particles. MIT Tech Talk 53(24):4–4Google Scholar