Encyclopedia of Wireless Networks

Living Edition
| Editors: Xuemin (Sherman) Shen, Xiaodong Lin, Kuan Zhang

Drug Delivery via Nanomachines

  • Yifan ChenEmail author
  • Yu Zhou
  • Neda Sharifi
  • Ross Murch
  • Geoffrey Holmes
Living reference work entry
DOI: https://doi.org/10.1007/978-3-319-32903-1_224-1



Drug delivery via nanomachines is one type of targeted drug delivery (TDD) technologies that delivers medicament to the designated area in vivo by using devices ranging in size from 0.1 to 10 μm and constructed of nanoscale components. Various terms such as nanomachine, nanorobot, nanobot, nanoid, nanite, and nanomite have been used to describe such devices. These nanomachines are loaded with drugs and targeted solely to diseased tissue under the manipulation and guidance of an external monitoring system. The purpose of this technology is to remarkably enhance locoregional therapies for disease treatment while reducing the side-effects of the drug on healthy cells.

Historical Background

In traditional drug delivery systems such as oral ingestion or intravascular injection, the medication is distributed throughout the body via the systemic blood circulation. For most therapeutic agents, only a small portion of the medication reaches the organ...

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Copyright information

© Springer Nature Switzerland AG 2018

Authors and Affiliations

  • Yifan Chen
    • 1
    Email author
  • Yu Zhou
    • 2
    • 3
  • Neda Sharifi
    • 1
  • Ross Murch
    • 3
  • Geoffrey Holmes
    • 1
  1. 1.The University of WaikatoHamiltonNew Zealand
  2. 2.Southern University of Science and TechnologyShenzhenChina
  3. 3.The Hong Kong University of Science and TechnologyHong KongChina

Section editors and affiliations

  • Adam Noel
    • 1
  1. 1.University of Warwick, UKWarwickUK