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Stratum Corneum Desquamation

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Agache's Measuring the Skin

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Abstract

Desquamation is a regular process participating in the stratum corneum self-renewal. It is globally correlated with the intercorneocyte cohesion and binding forces. Scaliness and xerosis represent frequent disorders of desquamation. The methods of assessment rely either on spontaneous or forced desquamation. Presently, the most common procedures involve specially designed tapes and cyanoacrylate skin surface strippings. The corneocytes are possibly stained in vivo using fluorescent or chromatic dyes. Assessments rely on visual, gravimetric, photometric, specular light reflectance, and image analysis methods.

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Abbreviations

ACD:

Adhesive-coated disk

CSSS:

Cyanoacrylate skin surface stripping

DC:

Dansyl chloride

DHA:

Dihydroxyacetone

ETT:

Epidermal turnover time

NMF:

Natural moisturizing factor

SC:

Stratum corneum

SCMI:

Skin capacitance mapping/imaging

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Author information

Authors and Affiliations

  1. Laboratory of Skin Bioengineering and Imaging (LABIC), Liège University, Liège, Belgium

    Gérald E. Piérard & Trinh Hermanns-Lê

  2. Service de Dermatopathologie, CHU du Sart Tilman, Liège, Belgium

    Gérald E. Piérard & Trinh Hermanns-Lê

  3. Department of Dermatopathology, Unilab Lg, University Hospital of Liège, Liège, Belgium

    Trinh Hermanns-Lê

  4. Laboratory of Skin Bioengineering and Imaging (LABIC), Department of Clinical Sciences, Liège University, Liège, Belgium

    Claudine Piérard-Franchimont

Authors
  1. Gérald E. Piérard
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  2. Trinh Hermanns-Lê
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  3. Claudine Piérard-Franchimont
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Corresponding author

Correspondence to Gérald E. Piérard .

Editor information

Editors and Affiliations

  1. Department of Dermatology, University Hospital of Besançon, Besançon, France

    Philippe Humbert

  2. Center for Study and Research on the Integuments, Department of Dermatology, University Hospital of Besançon, Besançon, France

    Ferial Fanian

  3. Department of Dermatology, School of Medicine, University of California, San Francisco, California, USA

    Howard I. Maibach

  4. Department of Dermatology, University Hospital of Besançon, Besançon, France

    Pierre Agache

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© 2017 Springer International Publishing Switzerland

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Piérard, G.E., Hermanns-Lê, T., Piérard-Franchimont, C. (2017). Stratum Corneum Desquamation. In: Humbert, P., Fanian, F., Maibach, H., Agache, P. (eds) Agache's Measuring the Skin. Springer, Cham. https://doi.org/10.1007/978-3-319-32383-1_25

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  • DOI: https://doi.org/10.1007/978-3-319-32383-1_25

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-32381-7

  • Online ISBN: 978-3-319-32383-1

  • eBook Packages: MedicineReference Module Medicine

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