Stratum Corneum Desquamation

  • Gérald E. Piérard
  • Trinh Hermanns-Lê
  • Claudine Piérard-Franchimont
Reference work entry
First Online:

Abstract

Desquamation is a regular process participating in the stratum corneum self-renewal. It is globally correlated with the intercorneocyte cohesion and binding forces. Scaliness and xerosis represent frequent disorders of desquamation. The methods of assessment rely either on spontaneous or forced desquamation. Presently, the most common procedures involve specially designed tapes and cyanoacrylate skin surface strippings. The corneocytes are possibly stained in vivo using fluorescent or chromatic dyes. Assessments rely on visual, gravimetric, photometric, specular light reflectance, and image analysis methods.

Keywords

Stratum corneum Corneocyte Corneodesmosome Xerosis Scaling Squamometry 

Abbreviations

ACD

Adhesive-coated disk

CSSS

Cyanoacrylate skin surface stripping

DC

Dansyl chloride

DHA

Dihydroxyacetone

ETT

Epidermal turnover time

NMF

Natural moisturizing factor

SC

Stratum corneum

SCMI

Skin capacitance mapping/imaging

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Copyright information

© Springer International Publishing Switzerland 2017

Authors and Affiliations

  • Gérald E. Piérard
    • 1
    • 2
  • Trinh Hermanns-Lê
    • 1
    • 2
    • 3
  • Claudine Piérard-Franchimont
    • 4
  1. 1.Laboratory of Skin Bioengineering and Imaging (LABIC)Liège UniversityLiègeBelgium
  2. 2.Service de DermatopathologieCHU du Sart TilmanLiègeBelgium
  3. 3.Department of Dermatopathology, Unilab LgUniversity Hospital of LiègeLiègeBelgium
  4. 4.Laboratory of Skin Bioengineering and Imaging (LABIC), Department of Clinical SciencesLiège UniversityLiègeBelgium

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