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Neonatology pp 717-730 | Cite as

Infants of Diabetic Mothers

  • Erin A. Osterholm
  • Jane E. Barthell
  • Michael K. Georgieff
Reference work entry

Abstract

Ten per cent of all pregnancies are complicated by gestational diabetes mellitus or preconceptional diabetes and, given the increased prevalence of obesity, this percentage is expected to rise over the next few years. While advances in maternal and neonatal medical care continue to improve the outcomes for infants born to mothers with glucose intolerance during pregnancy, the risks for spontaneous abortion, stillbirth, congenital malformations, and perinatal mortality still exist. Pregnancies of mothers with diabetes are given increased surveillance, as the multifaceted metabolic changes that occur in the mother affect fetal growth, glucose and iron metabolism, cardiac anatomy and function, transition to extrauterine life, placing the infant at risk for periconceptional, fetal, neonatal, and long-term morbidities. This chapter gives a perspective on the risks of glucose intolerance during pregnancies, neonatal complications, and long-term health sequelae of infants of diabetic mothers.

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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Erin A. Osterholm
    • 1
  • Jane E. Barthell
    • 2
  • Michael K. Georgieff
    • 1
  1. 1.Division of Neonatology, Department of Pediatrics Center for Neurobehavioral DevelopmentUniversity of MinnesotaMinneapolisUSA
  2. 2.Children’s Hospitals and Clinics of MinnesotaMinneapolisUSA

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