Encyclopedia of Pathology

Living Edition
| Editors: J.H.J.M. van Krieken

Proliferative Fasciitis and Proliferative Myositis

  • Albert SuurmeijerEmail author
Living reference work entry
DOI: https://doi.org/10.1007/978-3-319-28845-1_5457-1


Proliferative fasciitis is a mass-forming subcutaneous proliferation characterized by large ganglion-like cells and plump myofibroblastic/fibroblastic cells. Proliferative myositis has the same cellular composition but occurs within skeletal muscle.


Proliferative fasciitis develops most frequently in the upper extremities, particularly the forearms, followed by the lower extremities and trunk. Proliferative myositis arises predominantly in the trunk, shoulder girdles, and upper arms and less often in the thighs. By definition, proliferative fasciitis is subcutaneous and proliferative myositis is intramuscular.

Clinical Features

Both proliferative fasciitis and proliferative myositis characteristically grow rapidly and are usually excised within 2 months from the time they are first noted. Proliferative fasciitis almost always measures <5 cm and is most often <3 cm. Proliferative myositis may be slightly larger. Either lesion may be painful or tender; this is...

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References and Further Reading

  1. Chung, E. B., & Enzinger, F. M. (1975). Proliferative fasciitis. Cancer, 36(4), 1450–1458.CrossRefGoogle Scholar
  2. Enzinger, F. M., & Dulcey, F. (1967). Proliferative myositis. Report of thirty-three cases. Cancer, 20(12), 2213–2223.CrossRefGoogle Scholar
  3. el-Jabbour, J. N., Bennett, M. H., Burke, M. M., et al. (1991). Proliferative myositis. An immunohistochemical and ultrastructural study. The American Journal of Surgical Pathology, 15(7), 654–659.CrossRefGoogle Scholar
  4. Kern, W. H. (1960). Proliferative myositis; a pseudosarcomatous reaction to injury: A report of seven cases. Archives of Pathology, 69, 209–216.PubMedGoogle Scholar
  5. Lundgren, L., Kindblom, L. G., Willems, J., et al. (1992). Proliferative myositis and fasciitis. A light and electron microscopic, cytologic, DNA-cytometric and immunohistochemical study. APMIS, 100(5), 437–448.CrossRefGoogle Scholar
  6. Meis, J. M., & Enzinger, F. M. (1992). Proliferative fasciitis and myositis of childhood. The American Journal of Surgical Pathology, 16(4), 364–372.CrossRefGoogle Scholar
  7. Pagonidis, K., Raissaki, M., & Gourtsoyiannis, N. (2005). Proliferative myositis: Value of imaging. Journal of Computer Assisted Tomography, 29(1), 108–111.CrossRefGoogle Scholar
  8. Wong, N. L. (2002). Fine needle aspiration cytology of pseudosarcomatous reactive proliferative lesions of soft tissue. Acta Cytologica, 46(6), 1049–1055.CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.University of GroningenGroningenThe Netherlands