Encyclopedia of Pathology

Living Edition
| Editors: J.H.J.M. van Krieken

Elastofibroma

  • Marco GambarottiEmail author
Living reference work entry
DOI: https://doi.org/10.1007/978-3-319-28845-1_5377-1

Synonyms

Definition

A benign lesion characterized by abundant abnormal elastic fibers.

Clinical Features

  • Incidence

    It is considered a rare lesion, although the exact incidence is unknown as many cases represent incidental findings (Hisaoka and Nishio 2013).

  • Age

    It tends to affect elderly patient, with a peak in the seventh and eighth decades of life.

  • Sex

    Females are more frequently affected than males (Nagamine et al. 1982).

  • Site

    It generally arises in the soft tissue under the scapula, where it is supposed to be generated after repeated frictions between the scapula and the thoracic wall, with subsequent degeneration of the elastic fibers. Rarely, it can occur in other parts of the thoracic wall, in the extremities, limb girdles, gastrointestinal tract, or other viscera. The lesion can be bilateral or rarely multiple (Hisaoka and Nishio 2013).

  • Treatment

    Simple surgical excision is curative.

  • Outcome

    It is a benign lesion. Local recurrence can occur, after incomplete...

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References and Further Reading

  1. Hisaoka, M., & Hashimoto, H. (2006). Elastofibroma: Clonal fibrous proliferation with predominant CD34-positive cells. Virchows Archiv, 448(2), 195–199.CrossRefGoogle Scholar
  2. Hisaoka, M., & Nishio, J. (2013). Elastofibroma. In C. D. M. Fletcher, J. A. Bridge, P. C. W. Hogendoorn, & F. Mertens (Eds.), World Health Organization classification of tumours. Pathology and genetics of tumours of soft tissue and bone (pp. 53–54). IARC: Lyon.Google Scholar
  3. Nagamine, N., Nohara, Y., & Ito, E. (1982). Elastofibroma in Okinawa. A clinicopathologic study of 170 cases. Cancer, 50(9), 1794–1805.CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.IRCCS Istituto Ortopedico RizzoliBolognaItaly