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Encyclopedia of Pathology pp 1–3Cite as

Chondroid Lipoma

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  • First Online:

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Part of the book series: Encyclopedia of Pathology ((EP))

Definition

Chondroid lipoma (CL) is a benign adipocytic tumor combining adipocytic and cartilaginous features (Meis and Enzinger 1993; Thway et al. 2012).

Clinical Features

  • Incidence

    CL is extremely rare, with only few small series and single cases reported.

  • Age

    It occurs over a wide age range, but predominately in young adults, with a median of 30 years (Thway et al. 2012).

  • Sex

    CL arises more frequently in women (Thway et al. 2012).

  • Site

    Tumors are more frequently deep-seated and involve the proximal extremities and limb girdles. CL may also occur in the head and neck, particularly in the oral cavity (Meis and Enzinger 1993; Thway et al. 2012).

  • Treatment

    Surgical excision is the primary treatment for eradication of the tumor.

  • Outcome

    CL is benign and complete surgical removal is curative.

Macroscopy

CL appears as a well-circumscribed mass, measuring in average 4–5 cm (range 2–11), with a lobulated yellow cut surface and gelatinous tan-gray areas (Thway et al. 2012). Hemorrhage can...

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References

  • Ballaux, F., Debiec-Rychter, M., De Wever, I., & Sciot, R. (2004). Chondroid lipoma is characterized by t(11;16)(q13;p12–13). Virchows Archiv, 444(2), 208–210.

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  • Flucke, U., Tops, B. B., de Saint Aubain Somerhausen, N., Bras, J., Creytens, D. H., Küsters, B., Groenen, P. J., Verdijk, M. A., Suurmeijer, A. J., & Mentzel, T. (2013). Presence of C11orf95-MKL2 fusion is a consistent finding in chondroid lipomas: a study of eight cases. Histopathology, 62, 925–930.

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  • Gisselsson, D., Domanski, H. A., Höglund, M., Carlén, B., Mertens, F., Willén, H., & Mandahl, N. (1999). Unique cytological features and chromosome aberrations in chondroid lipoma: A case report based on fine-needle aspiration cytology, histopathology, electron microscopy, chromosome banding, and molecular cytogenetics. The American Journal of Surgical Pathology, 23, 1300–1304.

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  • Huang, D., Sumegi, J., Dal Cin, P., Reith, J. D., Yasuda, T., Nelson, M., Muirhead, D., & Bridge, J. A. (2010). C11orf95-MKL2 is the resulting fusion oncogene of t(11;16)(q13;p13) in chondroid lipoma. Genes, Chromosomes & Cancer, 49, 810–818.

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  • Meis, J. M., & Enzinger, F. M. (1993). Chondroid lipoma: a unique tumor simulating liposarcoma and myxoid chondrosarcoma. The American Journal of Surgical Pathology, 17, 1103–1112.

    Article  CAS  Google Scholar 

  • Thway, K., Flora, R. S., & Fisher, C. (2012). Chondroid lipoma: An update and review. Annals of Diagnostic Pathology, 16, 230–234.

    Article  Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Translational Research and of New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy

    Alessandro Franchi

Authors
  1. Alessandro Franchi
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Corresponding author

Correspondence to Alessandro Franchi .

Editor information

Editors and Affiliations

  1. NIJMEGEN, The Netherlands

    J.H.J.M. van Krieken

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Cite this entry

Franchi, A. (2020). Chondroid Lipoma. In: van Krieken, J. (eds) Encyclopedia of Pathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-28845-1_5365-1

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  • DOI: https://doi.org/10.1007/978-3-319-28845-1_5365-1

  • Received:

  • Accepted:

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-28845-1

  • Online ISBN: 978-3-319-28845-1

  • eBook Packages: Springer Reference MedicineReference Module Medicine

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