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The Pharmacological Activities of Glycyrrhizinic Acid (“Glycyrrhizin”) and Glycyrrhetinic Acid

  • Cedric Stephan Graebin
Living reference work entry
Part of the Reference Series in Phytochemistry book series (RSP)

Abstract

Glycyrrhizin or, more correctly, Glycyrrhizinic acid is a triterpenoid saponin obtained from the root and rhizome extracts of Licorice (Glycyrrhiza glabra), being commonly used as a sweetener, being reported as – at least – 30 times sweeter than sucrose. This natural product, along with its aglycone glycyrrhetinic acid, is known in the literature for its several pharmacological and biological activities. This chapter summarizes the activities reported in the literature for the saponin and its aglycone since 2010.

Keywords

Glycyrrhizinic acid Glycyrrhizin Glycyrrhetinic acid Glycyrrhiza glabra Liquorice 

Notes

Acknowledgments

This work is partly supported by grants from the Brazilian Government Science and Research Council (in Portuguese: Conselho Nacional de Pesquisa or CNPq) and the Rio de Janeiro State Research Foundation (Fundação de Apoio à Pesquisa do Estado do Rio de Janeiro or FAPERJ).

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© Springer International Publishing AG 2016

Authors and Affiliations

  1. 1.Chemistry DepartmentFederal Rural University of Rio de JaneiroSeropédicaBrazil

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