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Principles of Geriatric Surgery

  • Mark R. KatlicEmail author
  • Joann Coleman
Living reference work entry

Abstract

The world population is aging and the conditions that require surgery – atherosclerosis, cancer, arthritis, prostatism, cataract, pelvic floor disorders, and others – increase in incidence with increasing age. What do we know about surgery in the elderly that will help us improve our care of these conditions? Six general principles are useful for teaching purposes. These include the fact that the clinical presentation of surgical problems may be subtle or different from that of the general population; the elderly handle stress well but not severe stress due to lack of reserve; preoperative preparation and attention to detail are crucial; when these are lacking, as in emergency surgery, risk dramatically increases; and the results of elective surgery in the elderly are good in many centers and do not support prejudice against advanced age. Surgeons must become students of the physiologic changes that occur with aging and, guided by these few principles, apply this knowledge to daily clinical care. We owe it to our elders to become good geriatric surgeons and in so doing we will become better surgeons to patients of all ages.

Keywords

Geriatric Elderly Geriatric surgery Preoperative Perioperative Ageism Complications 

References

  1. 1.
    Smith OC (1907) Advanced age as a contraindication to operation. Med Rec (NY) 72:642–644Google Scholar
  2. 2.
    Ochsner A (1967) Is risk of operation too great in the elderly? Geriatrics 22:121–130PubMedGoogle Scholar
  3. 3.
    Alexander HR, Turnbull AD, Salamone J, Keefe D, Melendez J (1991) Upper abdominal cancer surgery in the very elderly. J Surg Oncol 47(2):82–86PubMedCrossRefGoogle Scholar
  4. 4.
    Bridges CR, Edwards FH, Peterson ED, Coombs LP, Ferguson TB (2003) Cardiac surgery in nonagenarians and centenarians. J Am Coll Surg 197(3):347–356; discussion 356–347PubMedCrossRefGoogle Scholar
  5. 5.
    Katlic MR (1985) Surgery in centenarians. JAMA 253(21):3139–3141PubMedCrossRefPubMedCentralGoogle Scholar
  6. 6.
    Ullery BW, Peterson JC, Milla F et al (2008) Cardiac surgery in select nonagenarians: should we or shouldn’t we? Ann Thorac Surg 85(3):854–860PubMedCrossRefGoogle Scholar
  7. 7.
    Cohen JR, Johnson H, Eaton S, Sterman H, Wise L (1988) Surgical procedures in patients during the tenth decade of life. Surgery 104(4):646–651PubMedPubMedCentralGoogle Scholar
  8. 8.
    Murashita T, Greason KL, Suri RM et al (2014) Aortic valve replacement for severe aortic valve stenosis in the nonagenarian patient. Ann Thorac Surg 98(5):1593–1597PubMedCrossRefPubMedCentralGoogle Scholar
  9. 9.
    Linn BS, Zeppa R (1987) Student attitudes about surgery in older patients before and after the surgical clerkship. Ann Surg 205(3):324–328PubMedPubMedCentralCrossRefGoogle Scholar
  10. 10.
    Thomas DR, Ritchie CS (1995) Preoperative assessment of older adults. J Am Geriatr Soc 43(7):811–821PubMedCrossRefPubMedCentralGoogle Scholar
  11. 11.
    Biancari F, Schifano P, Pighi M, Vasques F, Juvonen T, Vinco G (2013) Pooled estimates of immediate and late outcome of mitral valve surgery in octogenarians: a meta-analysis and meta-regression. J Cardiothorac Vasc Anesth 27(2):213–219PubMedCrossRefPubMedCentralGoogle Scholar
  12. 12.
    Jafari MD, Jafari F, Halabi WJ et al (2014) Colorectal cancer resections in the aging US population: a trend toward decreasing rates and improved outcomes. JAMA Surg 149(6):557–564PubMedCrossRefPubMedCentralGoogle Scholar
  13. 13.
    Goodney PP, Siewers AE, Stukel TA, Lucas FL, Wennberg DE, Birkmeyer JD (2002) Is surgery getting safer? National trends in operative mortality. J Am Coll Surg 195(2):219–227PubMedCrossRefPubMedCentralGoogle Scholar
  14. 14.
    Kiran RP, Attaluri V, Hammel J, Church J (2013) A novel nomogram accurately quantifies the risk of mortality in elderly patients undergoing colorectal surgery. Ann Surg 257(5):905–908PubMedCrossRefPubMedCentralGoogle Scholar
  15. 15.
    Storm-Dickerson TL, Horattas MC (2003) What have we learned over the past 20 years about appendicitis in the elderly? Am J Surg 185(3):198–201PubMedCrossRefPubMedCentralGoogle Scholar
  16. 16.
    Elangovan S (1996) Clinical and laboratory findings in acute appendicitis in the elderly. J Am Board Fam Pract 9(2):75–78PubMedPubMedCentralGoogle Scholar
  17. 17.
    Lau WY, Fan ST, Yiu TF, Chu KW, Lee JM (1985) Acute appendicitis in the elderly. Surg Gynecol Obstet 161(2):157–160PubMedPubMedCentralGoogle Scholar
  18. 18.
    Horattas MC, Guyton DP, Wu D (1990) A reappraisal of appendicitis in the elderly. Am J Surg 160(3):291–293PubMedCrossRefPubMedCentralGoogle Scholar
  19. 19.
    Soroken C, Samaras N, Samaras D, Huber P (2012) An unusual case of cholecystitis and liver abscesses in an older adult. J Am Geriatr Soc 60(1):160–161PubMedCrossRefPubMedCentralGoogle Scholar
  20. 20.
    Adedeji OA, McAdam WA (1996) Murphy’s sign, acute cholecystitis and elderly people. J R Coll Surg Edinb 41(2):88–89PubMedPubMedCentralGoogle Scholar
  21. 21.
    Hafif A, Gutman M, Kaplan O, Winkler E, Rozin RR, Skornick Y (1991) The management of acute cholecystitis in elderly patients. Am Surg 57(10):648–652PubMedPubMedCentralGoogle Scholar
  22. 22.
    Parker LJ, Vukov LF, Wollan PC (1997) Emergency department evaluation of geriatric patients with acute cholecystitis. Acad Emerg Med 4(1):51–55PubMedCrossRefPubMedCentralGoogle Scholar
  23. 23.
    Chen Y, Zheng M, Hu X et al (2008) Fever of unknown origin in elderly people: a retrospective study of 87 patients in China. J Am Geriatr Soc 56(1):182–184PubMedCrossRefPubMedCentralGoogle Scholar
  24. 24.
    Stewart L, Grifiss JM, Jarvis GA, Way LW (2008) Elderly patients have more severe biliary infections: influence of complement-killing and induction of TNFalpha production. Surgery 143(1):103–112PubMedCrossRefPubMedCentralGoogle Scholar
  25. 25.
    Magnuson TH, Ratner LE, Zenilman ME, Bender JS (1997) Laparoscopic cholecystectomy: applicability in the geriatric population. Am Surg 63(1):91–96PubMedPubMedCentralGoogle Scholar
  26. 26.
    Saunders K, Tompkins R, Longmire W Jr, Roslyn J (1991) Bile duct carcinoma in the elderly. A rationale for surgical management. Arch Surg 126(10):1186–1190; discussion 1190–1181PubMedCrossRefPubMedCentralGoogle Scholar
  27. 27.
    Hilton D, Iman N, Burke GJ et al (2001) Absence of abdominal pain in older persons with endoscopic ulcers: a prospective study. Am J Gastroenterol 96(2):380–384PubMedCrossRefPubMedCentralGoogle Scholar
  28. 28.
    Rabinovici R, Manny J (1991) Perforated duodenal ulcer in the elderly. Eur J Surg 157(2):121–125PubMedPubMedCentralGoogle Scholar
  29. 29.
    Tong K, Merchant R (2012) Nonacute acute abdomen in older adults. J Am Geriatr Soc 60(2):370–371PubMedCrossRefPubMedCentralGoogle Scholar
  30. 30.
    Mulcahy HE, Patchett SE, Daly L, O’Donoghue DP (1994) Prognosis of elderly patients with large bowel cancer. Br J Surg 81(5):736–738PubMedCrossRefPubMedCentralGoogle Scholar
  31. 31.
    Watters JM, Blakslee JM, March RJ, Redmond ML (1996) The influence of age on the severity of peritonitis. Can J Surg 39(2):142–146PubMedPubMedCentralGoogle Scholar
  32. 32.
    Tedesco P, Lobo E, Fisichella PM, Way LW, Patti MG (2006) Laparoscopic fundoplication in elderly patients with gastroesophageal reflux disease. Arch Surg 141(3):289–292; discussion 292PubMedCrossRefPubMedCentralGoogle Scholar
  33. 33.
    Pilotto A, Franceschi M, Leandro G et al (2006) Clinical features of reflux esophagitis in older people: a study of 840 consecutive patients. J Am Geriatr Soc 54(10):1537–1542PubMedCrossRefPubMedCentralGoogle Scholar
  34. 34.
    Knutson JW, Slavin RG (1995) Sinusitis in the aged. Optimal management strategies. Drugs Aging 7(4):310–316PubMedCrossRefPubMedCentralGoogle Scholar
  35. 35.
    Norman DC, Toledo SD (1992) Infections in elderly persons. An altered clinical presentation. Clin Geriatr Med 8(4):713–719PubMedCrossRefPubMedCentralGoogle Scholar
  36. 36.
    Koch WM, Patel H, Brennan J, Boyle JO, Sidransky D (1995) Squamous cell carcinoma of the head and neck in the elderly. Arch Otolaryngol Head Neck Surg 121(3):262–265PubMedCrossRefPubMedCentralGoogle Scholar
  37. 37.
    Ehlinger P, Fossion E, Vrielinck L (1993) Carcinoma of the oral cavity in patients over 75 years of age. Int J Oral Maxillofac Surg 22(4):218–220PubMedCrossRefPubMedCentralGoogle Scholar
  38. 38.
    Chigot JP, Menegaux F, Achrafi H (1995) Should primary hyperparathyroidism be treated surgically in elderly patients older than 75 years? Surgery 117(4):397–401PubMedCrossRefPubMedCentralGoogle Scholar
  39. 39.
    Thomas PC, Grigg M (1996) Carotid artery surgery in the octogenarian. Aust N Z J Surg 66(4):231–234PubMedCrossRefPubMedCentralGoogle Scholar
  40. 40.
    Canto JG, Fincher C, Kiefe CI et al (2002) Atypical presentations among medicare beneficiaries with unstable angina pectoris. Am J Cardiol 90(3):248–253PubMedCrossRefPubMedCentralGoogle Scholar
  41. 41.
    Heffernan DS, Thakkar RK, Monaghan SF et al (2010) Normal presenting vital signs are unreliable in geriatric blunt trauma victims. J Trauma 69(4):813–820PubMedCrossRefPubMedCentralGoogle Scholar
  42. 42.
    Hellmann DB (2003) Eurekapenia: a disease of medical residency training programs? Pharos Alpha Omega Alpha Honor Med Soc 66(2):24–26PubMedPubMedCentralGoogle Scholar
  43. 43.
    Durso SC (2004) A bipolar disorder: eurekaphoria, then discouragement. Pharos Alpha Omega Alpha Honor Med Soc 67(3):49PubMedPubMedCentralGoogle Scholar
  44. 44.
    Birim O, Zuydendorp HM, Maat AP, Kappetein AP, Eijkemans MJ, Bogers AJ (2003) Lung resection for non-small-cell lung cancer in patients older than 70: mortality, morbidity, and late survival compared with the general population. Ann Thorac Surg 76(6):1796–1801PubMedCrossRefPubMedCentralGoogle Scholar
  45. 45.
    Brock MV, Kim MP, Hooker CM et al (2004) Pulmonary resection in octogenarians with stage I nonsmall cell lung cancer: a 22-year experience. Ann Thorac Surg 77(1):271–277PubMedCrossRefPubMedCentralGoogle Scholar
  46. 46.
    Keagy BA, Pharr WF, Bowes DE, Wilcox BR (1984) A review of morbidity and mortality in elderly patients undergoing pulmonary resection. Am Surg 50(4):213–216PubMedPubMedCentralGoogle Scholar
  47. 47.
    Au J, El-Oakley R, Cameron EW (1994) Pneumonectomy for bronchogenic carcinoma in the elderly. Eur J Cardiothorac Surg 8(5):247–250PubMedCrossRefPubMedCentralGoogle Scholar
  48. 48.
    Miller DL, Deschamps C, Jenkins GD, Bernard A, Allen MS, Pairolero PC (2002) Completion pneumonectomy: factors affecting operative mortality and cardiopulmonary morbidity. Ann Thorac Surg 74(3):876–883; discussion 883–874PubMedCrossRefPubMedCentralGoogle Scholar
  49. 49.
    Rostad H, Naalsund A, Strand TE, Jacobsen R, Talleraas O, Norstein J (2005) Results of pulmonary resection for lung cancer in Norway, patients older than 70 years. Eur J Cardiothorac Surg 27(2):325–328PubMedCrossRefPubMedCentralGoogle Scholar
  50. 50.
    Demmy TL, Plante AJ, Nwogu CE, Takita H, Anderson TM (2004) Discharge independence with minimally invasive lobectomy. Am J Surg 188(6):698–702PubMedCrossRefPubMedCentralGoogle Scholar
  51. 51.
    Jaklitsch MT, DeCamp MM Jr, Liptay MJ et al (1996) Video-assisted thoracic surgery in the elderly. A review of 307 cases. Chest 110(3):751–758PubMedCrossRefPubMedCentralGoogle Scholar
  52. 52.
    Nomori H, Horio H, Fuyuno G, Kobayashi R, Yashima H (1996) Respiratory muscle strength after lung resection with special reference to age and procedures of thoracotomy. Eur J Cardiothorac Surg 10(5):352–358PubMedCrossRefPubMedCentralGoogle Scholar
  53. 53.
    Yim AP (1996) Thoracoscopic surgery in the elderly population. Surg Endosc 10(9):880–882PubMedCrossRefPubMedCentralGoogle Scholar
  54. 54.
    Cattaneo SM, Park BJ, Wilton AS et al (2008) Use of video-assisted thoracic surgery for lobectomy in the elderly results in fewer complications. Ann Thorac Surg 85(1):231–235; discussion 235–236PubMedCrossRefPubMedCentralGoogle Scholar
  55. 55.
    Patel HJ, Williams DM, Upchurch GR Jr et al (2008) A comparison of open and endovascular descending thoracic aortic repair in patients older than 75 years of age. Ann Thorac Surg 85(5):1597–1603; discussion 1603–1594PubMedCrossRefPubMedCentralGoogle Scholar
  56. 56.
    Jackson RS, Chang DC, Freischlag JA (2012) Comparison of long-term survival after open vs endovascular repair of intact abdominal aortic aneurysm among Medicare beneficiaries. JAMA 307(15):1621–1628PubMedCrossRefPubMedCentralGoogle Scholar
  57. 57.
    Tan HJ, Norton EC, Ye Z, Hafez KS, Gore JL, Miller DC (2012) Long-term survival following partial vs radical nephrectomy among older patients with early-stage kidney cancer. JAMA 307(15):1629–1635PubMedCrossRefPubMedCentralGoogle Scholar
  58. 58.
    Bergus BO, Feng WC, Bert AA, Singh AK (1992) Aortic valve replacement (AVR): influence of age on operative morbidity and mortality. Eur J Cardiothorac Surg 6(3):118–121PubMedCrossRefPubMedCentralGoogle Scholar
  59. 59.
    Salomon NW, Page US, Bigelow JC, Krause AH, Okies JE, Metzdorff MT (1991) Coronary artery bypass grafting in elderly patients. Comparative results in a consecutive series of 469 patients older than 75 years. J Thorac Cardiovasc Surg 101(2):209–217; discussion 217–208PubMedPubMedCentralGoogle Scholar
  60. 60.
    Lytle BW, Navia JL, Taylor PC et al (1997) Third coronary artery bypass operations: risks and costs. Ann Thorac Surg 64(5):1287–1295PubMedCrossRefPubMedCentralGoogle Scholar
  61. 61.
    Elayda MA, Hall RJ, Reul RM et al (1993) Aortic valve replacement in patients 80 years and older. Operative risks and long-term results. Circulation 88(5 Pt 2):II11–II16PubMedPubMedCentralGoogle Scholar
  62. 62.
    Mohammadi S, Kalavrouziotis D, Dagenais F, Voisine P, Charbonneau E (2012) Completeness of revascularization and survival among octogenarians with triple-vessel disease. Ann Thorac Surg 93(5):1432–1437PubMedCrossRefPubMedCentralGoogle Scholar
  63. 63.
    Girerd N, Magne J, Rabilloud M et al (2012) The impact of complete revascularization on long-term survival is strongly dependent on age. Ann Thorac Surg 94(4):1166–1172PubMedCrossRefPubMedCentralGoogle Scholar
  64. 64.
    Fortner JG, Lincer RM (1990) Hepatic resection in the elderly. Ann Surg 211(2):141–145PubMedPubMedCentralCrossRefGoogle Scholar
  65. 65.
    Fong Y, Blumgart LH, Fortner JG, Brennan MF (1995) Pancreatic or liver resection for malignancy is safe and effective for the elderly. Ann Surg 222(4):426–434; discussion 434–427PubMedPubMedCentralCrossRefGoogle Scholar
  66. 66.
    Escarce JJ, Shea JA, Chen W, Qian Z, Schwartz JS (1995) Outcomes of open cholecystectomy in the elderly: a longitudinal analysis of 21,000 cases in the prelaparoscopic era. Surgery 117(2):156–164PubMedCrossRefPubMedCentralGoogle Scholar
  67. 67.
    Tsujitani S, Katano K, Oka A, Ikeguchi M, Maeta M, Kaibara N (1996) Limited operation for gastric cancer in the elderly. Br J Surg 83(6):836–839PubMedCrossRefPubMedCentralGoogle Scholar
  68. 68.
    Gretschel S, Estevez-Schwarz L, Hunerbein M, Schneider U, Schlag PM (2006) Gastric cancer surgery in elderly patients. World J Surg 30(8):1468–1474PubMedCrossRefPubMedCentralGoogle Scholar
  69. 69.
    Okada M, Koike T, Higashiyama M, Yamato Y, Kodama K, Tsubota N (2006) Radical sublobar resection for small-sized non-small cell lung cancer: a multicenter study. J Thorac Cardiovasc Surg 132(4):769–775PubMedCrossRefPubMedCentralGoogle Scholar
  70. 70.
    Mery CM, Pappas AN, Bueno R et al (2005) Similar long-term survival of elderly patients with non-small cell lung cancer treated with lobectomy or wedge resection within the surveillance, epidemiology, and end results database. Chest 128(1):237–245PubMedCrossRefGoogle Scholar
  71. 71.
    Barbas AS, Turley RS, Ceppa EP et al (2012) Comparison of outcomes and the use of multimodality therapy in young and elderly people undergoing surgical resection of pancreatic cancer. J Am Geriatr Soc 60(2):344–350PubMedCrossRefGoogle Scholar
  72. 72.
    Lawrence VA, Hazuda HP, Cornell JE et al (2004) Functional independence after major abdominal surgery in the elderly. J Am Coll Surg 199(5):762–772PubMedCrossRefGoogle Scholar
  73. 73.
    Seymour DG, Vaz FG (1989) A prospective study of elderly general surgical patients: II. Post-operative complications. Age Ageing 18(5):316–326PubMedCrossRefGoogle Scholar
  74. 74.
    Dzankic S, Pastor D, Gonzalez C, Leung JM (2001) The prevalence and predictive value of abnormal preoperative laboratory tests in elderly surgical patients. Anesth Analg 93(2):301–308, 302nd contents pagePubMedGoogle Scholar
  75. 75.
    Vaporciyan AA, Merriman KW, Ece F et al (2002) Incidence of major pulmonary morbidity after pneumonectomy: association with timing of smoking cessation. Ann Thorac Surg 73(2):420–425; discussion 425–426PubMedCrossRefGoogle Scholar
  76. 76.
    Mizushima Y, Noto H, Sugiyama S et al (1997) Survival and prognosis after pneumonectomy for lung cancer in the elderly. Ann Thorac Surg 64(1):193–198PubMedCrossRefPubMedCentralGoogle Scholar
  77. 77.
    Reilly JJ (1997) Preparing for pulmonary resection: preoperative evaluation of patients. Chest 112(4 Suppl):206S–208SPubMedCrossRefPubMedCentralGoogle Scholar
  78. 78.
    Goldhaber SZ, Tapson VF (2004) A prospective registry of 5,451 patients with ultrasound-confirmed deep vein thrombosis. Am J Cardiol 93(2):259–262PubMedCrossRefPubMedCentralGoogle Scholar
  79. 79.
    Jacobs LG (2003) Prophylactic anticoagulation for venous thromboembolic disease in geriatric patients. J Am Geriatr Soc 51(10):1472–1478PubMedCrossRefPubMedCentralGoogle Scholar
  80. 80.
    Leppo JA (1995) Preoperative cardiac risk assessment for noncardiac surgery. Am J Cardiol 75(11):42D–51DPubMedCrossRefPubMedCentralGoogle Scholar
  81. 81.
    Biagini E, Elhendy A, Schinkel AF et al (2005) Long-term prediction of mortality in elderly persons by dobutamine stress echocardiography. J Gerontol A Biol Sci Med Sci 60(10):1333–1338PubMedCrossRefPubMedCentralGoogle Scholar
  82. 82.
    Snowden CP, Prentis J, Jacques B et al (2013) Cardiorespiratory fitness predicts mortality and hospital length of stay after major elective surgery in older people. Ann Surg 257(6):999–1004PubMedCrossRefPubMedCentralGoogle Scholar
  83. 83.
    Brunelli A, Pompili C, Berardi R et al (2012) Performance at preoperative stair-climbing test is associated with prognosis after pulmonary resection in stage I non-small cell lung cancer. Ann Thorac Surg 93(6):1796–1800PubMedCrossRefPubMedCentralGoogle Scholar
  84. 84.
    Pollock M, Roa J, Benditt J, Celli B (1993) Estimation of ventilatory reserve by stair climbing. A study in patients with chronic airflow obstruction. Chest 104(5):1378–1383PubMedCrossRefPubMedCentralGoogle Scholar
  85. 85.
    Brunelli A, Refai M, Xiume F et al (2008) Performance at symptom-limited stair-climbing test is associated with increased cardiopulmonary complications, mortality, and costs after major lung resection. Ann Thorac Surg 86(1):240–247; discussion 247–248PubMedCrossRefPubMedCentralGoogle Scholar
  86. 86.
    Win T, Jackson A, Groves AM, Sharples LD, Charman SC, Laroche CM (2006) Comparison of shuttle walk with measured peak oxygen consumption in patients with operable lung cancer. Thorax 61(1):57–60PubMedCrossRefPubMedCentralGoogle Scholar
  87. 87.
    Simonsick EM, Fan E, Fleg JL (2006) Estimating cardiorespiratory fitness in well-functioning older adults: treadmill validation of the long distance corridor walk. J Am Geriatr Soc 54(1):127–132PubMedCrossRefPubMedCentralGoogle Scholar
  88. 88.
    Robinson TN, Wu DS, Sauaia A et al (2013) Slower walking speed forecasts increased postoperative morbidity and 1-year mortality across surgical specialties. Ann Surg 258(4):582–588; discussion 588–590PubMedPubMedCentralGoogle Scholar
  89. 89.
    Afilalo J, Eisenberg MJ, Morin JF et al (2010) Gait speed as an incremental predictor of mortality and major morbidity in elderly patients undergoing cardiac surgery. J Am Coll Cardiol 56(20):1668–1676PubMedCrossRefPubMedCentralGoogle Scholar
  90. 90.
    Weinstein H, Bates AT, Spaltro BE, Thaler HT, Steingart RM (2007) Influence of preoperative exercise capacity on length of stay after thoracic cancer surgery. Ann Thorac Surg 84(1):197–202PubMedCrossRefPubMedCentralGoogle Scholar
  91. 91.
    Audisio RA, Pope D, Ramesh HS et al (2008) Shall we operate? Preoperative assessment in elderly cancer patients (PACE) can help. A SIOG surgical task force prospective study. Crit Rev Oncol Hematol 65(2):156–163PubMedCrossRefPubMedCentralGoogle Scholar
  92. 92.
    Internullo E, Moons J, Nafteux P et al (2008) Outcome after esophagectomy for cancer of the esophagus and GEJ in patients aged over 75 years. Eur J Cardiothorac Surg 33(6):1096–1104PubMedCrossRefPubMedCentralGoogle Scholar
  93. 93.
    Katlic MR (2013) The Holy Grail of geriatric surgery. Ann Surg 257(6):1005–1006PubMedCrossRefPubMedCentralGoogle Scholar
  94. 94.
    Iwamoto K, Ichiyama S, Shimokata K, Nakashima N (1993) Postoperative pneumonia in elderly patients: incidence and mortality in comparison with younger patients. Intern Med 32(4):274–277PubMedCrossRefPubMedCentralGoogle Scholar
  95. 95.
    Kwon AH, Matsui Y (2006) Laparoscopic cholecystectomy in patients aged 80 years and over. World J Surg 30(7):1204–1210PubMedCrossRefPubMedCentralGoogle Scholar
  96. 96.
    Landau O, Kott I, Deutsch AA, Stelman E, Reiss R (1992) Multifactorial analysis of septic bile and septic complications in biliary surgery. World J Surg 16(5):962–964; discussion 964–965PubMedCrossRefPubMedCentralGoogle Scholar
  97. 97.
    Meijer WS, Schmitz PI, Jeekel J (1990) Meta-analysis of randomized, controlled clinical trials of antibiotic prophylaxis in biliary tract surgery. Br J Surg 77(3):283–290PubMedCrossRefPubMedCentralGoogle Scholar
  98. 98.
    Watters JM, Clancey SM, Moulton SB, Briere KM, Zhu JM (1993) Impaired recovery of strength in older patients after major abdominal surgery. Ann Surg 218(3):380–390; discussion 390–383PubMedPubMedCentralCrossRefGoogle Scholar
  99. 99.
    Kudsk KA, Tolley EA, DeWitt RC et al (2003) Preoperative albumin and surgical site identify surgical risk for major postoperative complications. JPEN J Parenter Enteral Nutr 27(1):1–9PubMedCrossRefPubMedCentralGoogle Scholar
  100. 100.
    Souba WW (1997) Nutritional support. N Engl J Med 336(1):41–48PubMedCrossRefPubMedCentralGoogle Scholar
  101. 101.
    Bittner R, Butters M, Ulrich M, Uppenbrink S, Beger HG (1996) Total gastrectomy. Updated operative mortality and long-term survival with particular reference to patients older than 70 years of age. Ann Surg 224(1):37–42PubMedPubMedCentralCrossRefGoogle Scholar
  102. 102.
    Myrdal G, Gustafsson G, Lambe M, Horte LG, Stahle E (2001) Outcome after lung cancer surgery. Factors predicting early mortality and major morbidity. Eur J Cardiothorac Surg 20(4):694–699PubMedCrossRefPubMedCentralGoogle Scholar
  103. 103.
    Allen MS, Darling GE, Pechet TT et al (2006) Morbidity and mortality of major pulmonary resections in patients with early-stage lung cancer: initial results of the randomized, prospective ACOSOG Z0030 trial. Ann Thorac Surg 81(3):1013–1019; discussion 1019–1020PubMedCrossRefPubMedCentralGoogle Scholar
  104. 104.
    Cerfolio RJ, Bryant AS (2006) Survival and outcomes of pulmonary resection for non-small cell lung cancer in the elderly: a nested case-control study. Ann Thorac Surg 82(2):424–429; discussion 429–430PubMedCrossRefPubMedCentralGoogle Scholar
  105. 105.
    Coyle KA, Smith RB 3rd, Salam AA, Dodson TF, Chaikof EL, Lumsden AB (1994) Carotid endarterectomy in the octogenarian. Ann Vasc Surg 8(5):417–420PubMedCrossRefPubMedCentralGoogle Scholar
  106. 106.
    Maehara Y, Oshiro T, Oiwa H et al (1995) Gastric carcinoma in patients over 70 years of age. Br J Surg 82(1):102–105PubMedCrossRefPubMedCentralGoogle Scholar
  107. 107.
    Jougon JB, Ballester M, Duffy J et al (1997) Esophagectomy for cancer in the patient aged 70 years and older. Ann Thorac Surg 63(5):1423–1427PubMedCrossRefPubMedCentralGoogle Scholar
  108. 108.
    de Perrot M, Licker M, Reymond MA, Robert J, Spiliopoulos A (1999) Influence of age on operative mortality and long-term survival after lung resection for bronchogenic carcinoma. Eur Respir J 14(2):419–422PubMedCrossRefPubMedCentralGoogle Scholar
  109. 109.
    Okada M, Nishio W, Sakamoto T, Harada H, Uchino K, Tsubota N (2003) Long-term survival and prognostic factors of five-year survivors with complete resection of non-small cell lung carcinoma. J Thorac Cardiovasc Surg 126(2):558–562PubMedCrossRefPubMedCentralGoogle Scholar
  110. 110.
    Thomas P, Sielezenff I, Rajni J, Giridicilli R, Fuentes P (1993) Is lung cancer resection justified in patients aged over 70 years? Eur J Cardiothorac Surg 7:246–251PubMedCrossRefPubMedCentralGoogle Scholar
  111. 111.
    Turrentine FE, Wang H, Simpson VB, Jones RS (2006) Surgical risk factors, morbidity, and mortality in elderly patients. J Am Coll Surg 203(6):865–877PubMedCrossRefPubMedCentralGoogle Scholar
  112. 112.
    Keller SM, Markovitz LJ, Wilder JR, Aufses AH Jr (1987) Emergency and elective surgery in patients over age 70. Am Surg 53(11):636–640PubMedPubMedCentralGoogle Scholar
  113. 113.
    Bingener J, Richards ML, Schwesinger WH, Strodel WE, Sirinek KR (2003) Laparoscopic cholecystectomy for elderly patients: gold standard for golden years? Arch Surg 138(5):531–535; discussion 535–536PubMedCrossRefPubMedCentralGoogle Scholar
  114. 114.
    Tambyraja AL, Kumar S, Nixon SJ (2004) Outcome of laparoscopic cholecystectomy in patients 80 years and older. World J Surg 28(8):745–748PubMedCrossRefPubMedCentralGoogle Scholar
  115. 115.
    Tsai TP, Chaux A, Matloff JM et al (1994) Ten-year experience of cardiac surgery in patients aged 80 years and over. Ann Thorac Surg 58(2):445–450; discussion 450–441PubMedCrossRefPubMedCentralGoogle Scholar
  116. 116.
    Tseng EE, Lee CA, Cameron DE et al (1997) Aortic valve replacement in the elderly. Risk factors and long-term results. Ann Surg 225(6):793–802; discussion 802–794PubMedPubMedCentralCrossRefGoogle Scholar
  117. 117.
    Bender JS, Magnuson TH, Zenilman ME et al (1996) Outcome following colon surgery in the octagenarian. Am Surg 62(4):276–279PubMedPubMedCentralGoogle Scholar
  118. 118.
    Spivak H, Maele DV, Friedman I, Nussbaum M (1996) Colorectal surgery in octogenarians. J Am Coll Surg 183(1):46–50PubMedPubMedCentralGoogle Scholar
  119. 119.
    Gregg ZA, Dao HE, Schechter S, Shah N (2014) Paracolostomy hernia repair: who and when? J Am Coll Surg 218(6):1105–1112PubMedCrossRefPubMedCentralGoogle Scholar
  120. 120.
    Sisto D, Hoffman D, Frater RW (1993) Isolated coronary artery bypass grafting in one hundred octogenarian patients. J Thorac Cardiovasc Surg 106(5):940–942PubMedPubMedCentralGoogle Scholar
  121. 121.
    Logeais Y, Langanay T, Roussin R et al (1994) Surgery for aortic stenosis in elderly patients. A study of surgical risk and predictive factors. Circulation 90(6):2891–2898PubMedCrossRefPubMedCentralGoogle Scholar
  122. 122.
    Maurice-Williams RS, Kitchen ND (1992) Intracranial tumours in the elderly: the effect of age on the outcome of first time surgery for meningiomas. Br J Neurosurg 6(2):131–137PubMedCrossRefPubMedCentralGoogle Scholar
  123. 123.
    Tan KY, Chen CM, Ng C, Tan SM, Tay KH (2006) Which octogenarians do poorly after major open abdominal surgery in our Asian population? World J Surg 30(4):547–552PubMedCrossRefPubMedCentralGoogle Scholar
  124. 124.
    Adam DJ, Craig SR, Sang CT, Cameron EW, Walker WS (1996) Esophagectomy for carcinoma in the octogenarian. Ann Thorac Surg 61(1):190–194PubMedCrossRefPubMedCentralGoogle Scholar
  125. 125.
    Mathisen DJ, Grillo HC, Wilkins EW Jr, Moncure AC, Hilgenberg AD (1988) Transthoracic esophagectomy: a safe approach to carcinoma of the esophagus. Ann Thorac Surg 45(2):137–143PubMedCrossRefPubMedCentralGoogle Scholar
  126. 126.
    Bandoh T, Isoyama T, Toyoshima H (1991) Total gastrectomy for gastric cancer in the elderly. Surgery 109(2):136–142PubMedPubMedCentralGoogle Scholar
  127. 127.
    Katz NM, Chase GA (1997) Risks of cardiac operations for elderly patients: reduction of the age factor. Ann Thorac Surg 63(5):1309–1314PubMedCrossRefPubMedCentralGoogle Scholar
  128. 128.
    Bernstein EF, Dilley RB, Randolph HF 3rd. (1988) The improving long-term outlook for patients over 70 years of age with abdominal aortic aneurysms. Ann Surg 207(3):318–322PubMedPubMedCentralCrossRefGoogle Scholar
  129. 129.
    Lo CY, van Heerden JA, Grant CS, Soreide JA, Warner MA, Ilstrup DM (1996) Adrenal surgery in the elderly: too risky? World J Surg 20(3):368–373; discussion 374PubMedCrossRefPubMedCentralGoogle Scholar
  130. 130.
    Giannice R, Foti E, Poerio A, Marana E, Mancuso S, Scambia G (2004) Perioperative morbidity and mortality in elderly gynecological oncological patients (>/= 70 Years) by the American Society of Anesthesiologists physical status classes. Ann Surg Oncol 11(2):219–225PubMedCrossRefPubMedCentralGoogle Scholar
  131. 131.
    Henry L, Halpin L, Hunt S, Holmes SD, Ad N (2012) Patient disposition and long-term outcomes after valve surgery in octogenarians. Ann Thorac Surg 94(3):744–750PubMedCrossRefGoogle Scholar
  132. 132.
    Period life table (2013) Actuarial life table. http://www.ssa.gov/OACT/STATS/table4c6.html. Accessed 11 Aug 2016
  133. 133.
    Heron M (2016) Deaths: leading causes for 2014. Natl Vital Stat Rep 65(5):1–95PubMedGoogle Scholar
  134. 134.
    Nugent WC, Edney MT, Hammerness PG, Dain BJ, Maurer LH, Rigas JR (1997) Non-small cell lung cancer at the extremes of age: impact on diagnosis and treatment. Ann Thorac Surg 63(1):193–197PubMedCrossRefGoogle Scholar
  135. 135.
    Beckett P, Callister M, Tata LJ et al (2012) Clinical management of older people with non-small cell lung cancer in England. Thorax 67(9):836–839PubMedCrossRefGoogle Scholar
  136. 136.
    Riaz SP, Linklater KM, Page R, Peake MD, Moller H, Luchtenborg M (2012) Recent trends in resection rates among non-small cell lung cancer patients in England. Thorax 67(9):811–814PubMedCrossRefGoogle Scholar
  137. 137.
    Kuo CW, Chen YM, Chao JY, Tsai CM, Perng RP (2000) Non-small cell lung cancer in very young and very old patients. Chest 117(2):354–357PubMedCrossRefGoogle Scholar
  138. 138.
    Fruh M, Rolland E, Pignon JP et al (2008) Pooled analysis of the effect of age on adjuvant cisplatin-based chemotherapy for completely resected non-small-cell lung cancer. J Clin Oncol 26(21):3573–3581PubMedCrossRefGoogle Scholar
  139. 139.
    Cress RD, O’Malley CD, Leiserowitz GS, Campleman SL (2003) Patterns of chemotherapy use for women with ovarian cancer: a population-based study. J Clin Oncol 21(8):1530–1535PubMedCrossRefGoogle Scholar
  140. 140.
    Moore DH (1994) Ovarian cancer in the elderly patient. Oncology (Huntingt) 8(12):21–25; discussion 25, 29–30Google Scholar
  141. 141.
    Edmonson JH, Su J, Krook JE (1993) Treatment of ovarian cancer in elderly women. Mayo Clinic-North Central Cancer Treatment Group studies. Cancer 71(2 Suppl):615–617PubMedGoogle Scholar
  142. 142.
    Singletary SE, Shallenberger R, Guinee VF (1993) Breast cancer in the elderly. Ann Surg 218(5):667–671PubMedPubMedCentralCrossRefGoogle Scholar
  143. 143.
    Wanebo HJ, Cole B, Chung M et al (1997) Is surgical management compromised in elderly patients with breast cancer? Ann Surg 225(5):579–586; discussion 586–579PubMedPubMedCentralCrossRefGoogle Scholar
  144. 144.
    Swanson RS, Sawicka J, Wood WC (1991) Treatment of carcinoma of the breast in the older geriatric patient. Surg Gynecol Obstet 173(6):465–469PubMedPubMedCentralGoogle Scholar
  145. 145.
    van Dalsen AD, de Vries JE (1995) Treatment of breast cancer in elderly patients. J Surg Oncol 60(2):80–82PubMedCrossRefPubMedCentralGoogle Scholar
  146. 146.
    Guadagnoli E, Shapiro C, Gurwitz JH et al (1997) Age-related patterns of care: evidence against ageism in the treatment of early-stage breast cancer. J Clin Oncol 15(6):2338–2344PubMedCrossRefPubMedCentralGoogle Scholar
  147. 147.
    Hebert-Croteau N, Brisson J, Latreille J, Blanchette C, Deschenes L (1999) Compliance with consensus recommendations for the treatment of early stage breast carcinoma in elderly women. Cancer 85(5):1104–1113PubMedCrossRefPubMedCentralGoogle Scholar
  148. 148.
    Hurria A, Hurria A, Zuckerman E et al (2006) A prospective, longitudinal study of the functional status and quality of life of older patients with breast cancer receiving adjuvant chemotherapy. J Am Geriatr Soc 54(7):1119–1124PubMedCrossRefGoogle Scholar
  149. 149.
    Silliman RA, Ganz PA (2006) Adjuvant chemotherapy use and outcomes in older women with breast cancer: what have we learned? J Clin Oncol 24(18):2697–2699PubMedCrossRefGoogle Scholar
  150. 150.
    Bilimoria KY, Stewart AK, Palis BE, Bentrem DJ, Talamonti MS, Ko CY (2008) Adequacy and importance of lymph node evaluation for colon cancer in the elderly. J Am Coll Surg 206(2):247–254PubMedCrossRefGoogle Scholar
  151. 151.
    Pokorney SD, Miller AL, Chen AY et al (2015) Implantable cardioverter-defibrillator use among medicare patients with low ejection fraction after acute myocardial infarction. JAMA 313(24):2433–2440PubMedCrossRefGoogle Scholar
  152. 152.
    Chalmers RT, Stonebridge PA, John TG, Murie JA (1993) Abdominal aortic aneurysm in the elderly. Br J Surg 80(9):1122–1123PubMedCrossRefGoogle Scholar
  153. 153.
    Blanche C, Matloff JM, Denton TA et al (1997) Cardiac operations in patients 90 years of age and older. Ann Thorac Surg 63(6):1685–1690PubMedCrossRefGoogle Scholar
  154. 154.
    Pierard S, Seldrum S, de Meester C et al Incidence, determinants, and prognostic impact of operative refusal or denial in octogenarians with severe aortic stenosis. Ann Thorac Surg 91(4):1107–1112PubMedCrossRefGoogle Scholar
  155. 155.
    Riall TS, Sheffield KM, Kuo YF, Townsend CM Jr, Goodwin JS (2011) Resection benefits older adults with locoregional pancreatic cancer despite greater short-term morbidity and mortality. J Am Geriatr Soc 59(4):647–654PubMedPubMedCentralCrossRefGoogle Scholar
  156. 156.
    Owonikoko TK, Ragin CC, Belani CP et al (2007) Lung cancer in elderly patients: an analysis of the surveillance, epidemiology, and end results database. J Clin Oncol 25(35):5570–5577PubMedCrossRefGoogle Scholar
  157. 157.
    Koppert LB, Lemmens VE, Coebergh JW et al (2012) Impact of age and co-morbidity on surgical resection rate and survival in patients with oesophageal and gastric cancer. Br J Surg 99(12):1693–1700PubMedCrossRefGoogle Scholar
  158. 158.
    Finlayson E, Fan Z, Birkmeyer JD (2007) Outcomes in octogenarians undergoing high-risk cancer operation: a national study. J Am Coll Surg 205(6):729–734PubMedCrossRefGoogle Scholar
  159. 159.
    Moskovitz AH, Rizk NP, Venkatraman E et al (2006) Mortality increases for octogenarians undergoing esophagogastrectomy for esophageal cancer. Ann Thorac Surg 82(6):2031–2036; discussion 2036PubMedCrossRefGoogle Scholar
  160. 160.
    Ngaage DL, Cowen ME, Griffin S, Guvendik L, Cale AR (2008) Early neurological complications after coronary artery bypass grafting and valve surgery in octogenarians. Eur J Cardiothorac Surg 33(4):653–659PubMedCrossRefGoogle Scholar
  161. 161.
    Leo F, Scanagatta P, Baglio P et al (2007) The risk of pneumonectomy over the age of 70. A case-control study. Eur J Cardiothorac Surg 31(5):780–782PubMedCrossRefGoogle Scholar
  162. 162.
    Lee JD, Bonaros N, Hong PT et al (2013) Factors influencing hospital length of stay after robotic totally endoscopic coronary artery bypass grafting. Ann Thorac Surg 95(3):813–818PubMedCrossRefGoogle Scholar
  163. 163.
    Barnett SD, Halpin LS, Speir AM et al (2003) Postoperative complications among octogenarians after cardiovascular surgery. Ann Thorac Surg 76(3):726–731PubMedCrossRefGoogle Scholar
  164. 164.
    Jarvinen O, Huhtala H, Laurikka J, Tarkka MR (2003) Higher age predicts adverse outcome and readmission after coronary artery bypass grafting. World J Surg 27(12):1317–1322PubMedCrossRefGoogle Scholar
  165. 165.
    Lightner AM, Glasgow RE, Jordan TH et al (2004) Pancreatic resection in the elderly. J Am Coll Surg 198(5):697–706PubMedCrossRefGoogle Scholar
  166. 166.
    Sosa JA, Mehta PJ, Wang TS, Boudourakis L, Roman SA (2008) A population-based study of outcomes from thyroidectomy in aging Americans: at what cost? J Am Coll Surg 206(3):1097–1105PubMedCrossRefGoogle Scholar
  167. 167.
    Mamoun NF, Xu M, Sessler DI, Sabik JF, Bashour CA (2008) Propensity matched comparison of outcomes in older and younger patients after coronary artery bypass graft surgery. Ann Thorac Surg 85(6):1974–1979PubMedCrossRefGoogle Scholar
  168. 168.
    Fraioli B, Pastore FS, Signoretti S, De Caro GM, Giuffre R (1999) The surgical treatment of pituitary adenomas in the eighth decade. Surg Neurol 51(3):261–266; discussion 266–267PubMedCrossRefGoogle Scholar
  169. 169.
    Derks W, De Leeuw JR, Hordijk GJ, Winnubst JA (2003) Elderly patients with head and neck cancer: short-term effects of surgical treatment on quality of life. Clin Otolaryngol 28(5):399–405PubMedCrossRefGoogle Scholar
  170. 170.
    Uruno T, Miyauchi A, Shimizu K et al (2005) Favorable surgical results in 433 elderly patients with papillary thyroid cancer. World J Surg 29(11):1497–1501; discussion 1502–1493PubMedCrossRefGoogle Scholar
  171. 171.
    Salameh JR, Myers JL, Mukherjee D (2002) Carotid endarterectomy in elderly patients: low complication rate with overnight stay. Arch Surg 137(11):1284–1287; discussion 1288PubMedCrossRefGoogle Scholar
  172. 172.
    Durward QJ, Ragnarsson TS, Reeder RF, Case JL, Hughes CA (2005) Carotid endarterectomy in nonagenarians. Arch Surg 140(7):625–628; discussion 628PubMedCrossRefGoogle Scholar
  173. 173.
    Beauford RB, Goldstein DJ, Sardari FF et al (2003) Multivessel off-pump revascularization in octogenarians: early and midterm outcomes. Ann Thorac Surg 76(1):12–17; discussion 17PubMedCrossRefGoogle Scholar
  174. 174.
    Chiappini B, Camurri N, Loforte A, Di Marco L, Di Bartolomeo R, Marinelli G (2004) Outcome after aortic valve replacement in octogenarians. Ann Thorac Surg 78(1):85–89PubMedCrossRefGoogle Scholar
  175. 175.
    Collart F, Feier H, Kerbaul F et al (2005) Valvular surgery in octogenarians: operative risks factors, evaluation of Euroscore and long term results. Eur J Cardiothorac Surg 27(2):276–280PubMedCrossRefPubMedCentralGoogle Scholar
  176. 176.
    Ferguson TB Jr, Hammill BG, Peterson ED, DeLong ER, Grover FL (2002) A decade of change – risk profiles and outcomes for isolated coronary artery bypass grafting procedures, 1990–1999: a report from the STS National Database Committee and the Duke Clinical Research Institute. Society of Thoracic Surgeons. Ann Thorac Surg 73(2):480–489; discussion 489–490PubMedCrossRefPubMedCentralGoogle Scholar
  177. 177.
    Huber CH, Goeber V, Berdat P, Carrel T, Eckstein F (2007) Benefits of cardiac surgery in octogenarians – a postoperative quality of life assessment. Eur J Cardiothorac Surg 31(6):1099–1105PubMedCrossRefPubMedCentralGoogle Scholar
  178. 178.
    Rice DC, Correa AM, Vaporciyan AA et al (2005) Preoperative chemoradiotherapy prior to esophagectomy in elderly patients is not associated with increased morbidity. Ann Thorac Surg 79(2):391–397; discussion 391–397PubMedCrossRefPubMedCentralGoogle Scholar
  179. 179.
    Ruol A, Portale G, Zaninotto G et al (2007a) Results of esophagectomy for esophageal cancer in elderly patients: age has little influence on outcome and survival. J Thorac Cardiovasc Surg 133(5):1186–1192PubMedCrossRefPubMedCentralGoogle Scholar
  180. 180.
    Ruol A, Portale G, Castoro C et al (2007b) Effects of neoadjuvant therapy on perioperative morbidity in elderly patients undergoing esophagectomy for esophageal cancer. Ann Surg Oncol 14(11):3243–3250PubMedCrossRefPubMedCentralGoogle Scholar
  181. 181.
    Poon RT, Law SY, Chu KM, Branicki FJ, Wong J (1998) Esophagectomy for carcinoma of the esophagus in the elderly: results of current surgical management. Ann Surg 227(3):357–364PubMedPubMedCentralCrossRefGoogle Scholar
  182. 182.
    Kunisaki C, Akiyama H, Nomura M et al (2006) Comparison of surgical outcomes of gastric cancer in elderly and middle-aged patients. Am J Surg 191(2):216–224PubMedCrossRefPubMedCentralGoogle Scholar
  183. 183.
    Biondi A, Cananzi FC, Persiani R et al (2012) The road to curative surgery in gastric cancer treatment: a different path in the elderly? J Am Coll Surg 215(6):858–867PubMedCrossRefPubMedCentralGoogle Scholar
  184. 184.
    Avital S, Kashtan H, Hadad R, Werbin N (1997) Survival of colorectal carcinoma in the elderly. A prospective study of colorectal carcinoma and a five-year follow-up. Dis Colon Rectum 40(5):523–529PubMedCrossRefPubMedCentralGoogle Scholar
  185. 185.
    Barrier A, Ferro L, Houry S, Lacaine F, Huguier M (2003) Rectal cancer surgery in patients more than 80 years of age. Am J Surg 185(1):54–57PubMedCrossRefPubMedCentralGoogle Scholar
  186. 186.
    Law WL, Choi HK, Ho JW, Lee YM, Seto CL (2006) Outcomes of surgery for mid and distal rectal cancer in the elderly. World J Surg 30(4):598–604PubMedCrossRefPubMedCentralGoogle Scholar
  187. 187.
    Aldrighetti L, Arru M, Caterini R et al (2003) Impact of advanced age on the outcome of liver resection. World J Surg 27(10):1149–1154PubMedCrossRefPubMedCentralGoogle Scholar
  188. 188.
    Cescon M, Grazi GL, Del Gaudio M et al (2003) Outcome of right hepatectomies in patients older than 70 years. Arch Surg 138(5):547–552PubMedCrossRefPubMedCentralGoogle Scholar
  189. 189.
    Ferrero A, Vigano L, Polastri R et al (2005) Hepatectomy as treatment of choice for hepatocellular carcinoma in elderly cirrhotic patients. World J Surg 29(9):1101–1105PubMedCrossRefPubMedCentralGoogle Scholar
  190. 190.
    Menon KV, Al-Mukhtar A, Aldouri A, Prasad RK, Lodge PA, Toogood GJ (2006) Outcomes after major hepatectomy in elderly patients. J Am Coll Surg 203(5):677–683PubMedCrossRefPubMedCentralGoogle Scholar
  191. 191.
    Sohn TA, Yeo CJ, Cameron JL et al (1998) Should pancreaticoduodenectomy be performed in octogenarians? J Gastrointest Surg 2(3):207–216PubMedCrossRefPubMedCentralGoogle Scholar
  192. 192.
    Petrowsky H, Clavien PA (2005) Should we deny surgery for malignant hepato-pancreatico-biliary tumors to elderly patients? World J Surg 29(9):1093–1100PubMedCrossRefPubMedCentralGoogle Scholar
  193. 193.
    Geisler JP, Geisler HE (1994) Radical hysterectomy in patients 65 years of age and older. Gynecol Oncol 53(2):208–211PubMedCrossRefPubMedCentralGoogle Scholar
  194. 194.
    Anderson JG, Wixson RL, Tsai D, Stulberg SD, Chang RW (1996) Functional outcome and patient satisfaction in total knee patients over the age of 75. J Arthroplast 11(7):831–840CrossRefGoogle Scholar
  195. 195.
    Wurtz LD, Feinberg JR, Capello WN, Meldrum R, Kay PJ (2003) Elective primary total hip arthroplasty in octogenarians. J Gerontol A Biol Sci Med Sci 58(5):M468–M471PubMedCrossRefPubMedCentralGoogle Scholar
  196. 196.
    Hamel MB, Toth M, Legedza A, Rosen MP (2008) Joint replacement surgery in elderly patients with severe osteoarthritis of the hip or knee: decision making, postoperative recovery, and clinical outcomes. Arch Intern Med 168(13):1430–1440PubMedCrossRefPubMedCentralGoogle Scholar
  197. 197.
    Malata CM, Cooter RD, Batchelor AG, Simpson KH, Browning FS, Kay SP (1996) Microvascular free-tissue transfers in elderly patients: the leeds experience. Plast Reconstr Surg 98(7):1234–1241PubMedCrossRefGoogle Scholar
  198. 198.
    George TJ, Kilic A, Beaty CA, Conte JV, Mandal K, Shah AS (2013) Septuagenarians bridged to heart transplantation with a ventricular assist device have outcomes similar to younger patients. Ann Thorac Surg 95(4):1251–1260; discussion 1260–1251PubMedPubMedCentralCrossRefGoogle Scholar
  199. 199.
    Morgan JA, John R, Weinberg AD et al (2003) Long-term results of cardiac transplantation in patients 65 years of age and older: a comparative analysis. Ann Thorac Surg 76(6):1982–1987PubMedCrossRefGoogle Scholar
  200. 200.
    Goldstein DJ, Bello R, Shin JJ et al (2012) Outcomes of cardiac transplantation in septuagenarians. J Heart Lung Transplant 31(7):679–685PubMedCrossRefPubMedCentralGoogle Scholar
  201. 201.
    Mahidhara R, Bastani S, Ross DJ et al (2008) Lung transplantation in older patients? J Thorac Cardiovasc Surg 135(2):412–420PubMedCrossRefPubMedCentralGoogle Scholar
  202. 202.
    Minor ME, Ellozy S, Carroccio A et al (2004) Endovascular aortic aneurysm repair in the octogenarian: is it worthwhile? Arch Surg 139(3):308–314PubMedCrossRefPubMedCentralGoogle Scholar
  203. 203.
    St Peter SD, Craft RO, Tiede JL, Swain JM (2005) Impact of advanced age on weight loss and health benefits after laparoscopic gastric bypass. Arch Surg 140(2):165–168PubMedCrossRefPubMedCentralGoogle Scholar
  204. 204.
    Chautard J, Alves A, Zalinski S, Bretagnol F, Valleur P, Panis Y (2008) Laparoscopic colorectal surgery in elderly patients: a matched case-control study in 178 patients. J Am Coll Surg 206(2):255–260PubMedCrossRefPubMedCentralGoogle Scholar
  205. 205.
    Gianetta E, de Cian F, Cuneo S et al (1997) Hernia repair in elderly patients. Br J Surg 84(7):983–985PubMedCrossRefPubMedCentralGoogle Scholar
  206. 206.
    Amemiya T, Oda K, Ando M et al (2007) Activities of daily living and quality of life of elderly patients after elective surgery for gastric and colorectal cancers. Ann Surg 246(2):222–228PubMedPubMedCentralCrossRefGoogle Scholar
  207. 207.
    Zierer A, Melby SJ, Lubahn JG, Sicard GA, Damiano RJ Jr, Moon MR (2006) Elective surgery for thoracic aortic aneurysms: late functional status and quality of life. Ann Thorac Surg 82(2):573–578PubMedCrossRefPubMedCentralGoogle Scholar
  208. 208.
    de Vincentiis C, Kunkl AB, Trimarchi S et al (2008) Aortic valve replacement in octogenarians: is biologic valve the unique solution? Ann Thorac Surg 85(4):1296–1301PubMedCrossRefPubMedCentralGoogle Scholar
  209. 209.
    Vicchio M, Della Corte A, De Santo LS et al (2008) Tissue versus mechanical prostheses: quality of life in octogenarians. Ann Thorac Surg 85(4):1290–1295PubMedCrossRefPubMedCentralGoogle Scholar
  210. 210.
    Dunlop WE, Rosenblood L, Lawrason L, Birdsall L, Rusnak CH (1993) Effects of age and severity of illness on outcome and length of stay in geriatric surgical patients. Am J Surg 165(5):577–580PubMedCrossRefPubMedCentralGoogle Scholar
  211. 211.
    Akoh JA, Mathew AM, Chalmers JW, Finlayson A, Auld GD (1994) Audit of major gastrointestinal surgery in patients aged 80 years or over. J R Coll Surg Edinb 39(4):208–213PubMedPubMedCentralGoogle Scholar
  212. 212.
    Battafarano RJ, Piccirillo JF, Meyers BF et al (2002) Impact of comorbidity on survival after surgical resection in patients with stage I non-small cell lung cancer. J Thorac Cardiovasc Surg 123(2):280–287PubMedCrossRefPubMedCentralGoogle Scholar
  213. 213.
    Mehta RH, Eagle KA, Coombs LP et al (2002) Influence of age on outcomes in patients undergoing mitral valve replacement. Ann Thorac Surg 74(5):1459–1467PubMedCrossRefPubMedCentralGoogle Scholar
  214. 214.
    Muravchick S (2000) Anesthesia for the elderly. In: Miller RD (ed) Anesthesia, 5th edn. Churchill Livingston, Philadelphia, pp 2140–2156Google Scholar
  215. 215.
    Barzan L, Veronesi A, Caruso G et al (1990) Head and neck cancer and ageing: a retrospective study in 438 patients. J Laryngol Otol 104(8):634–640PubMedCrossRefPubMedCentralGoogle Scholar
  216. 216.
    Gupta R, Kawashima T, Ryu M, Okada T, Cho A, Takayama W (2004) Role of curative resection in octogenarians with malignancy. Am J Surg 188(3):282–287PubMedCrossRefPubMedCentralGoogle Scholar
  217. 217.
    Martin RC 2nd, Jaques DP, Brennan MF, Karpeh M (2002) Extended local resection for advanced gastric cancer: increased survival versus increased morbidity. Ann Surg 236(2):159–165PubMedPubMedCentralCrossRefGoogle Scholar
  218. 218.
    Siegelmann-Danieli N, Khandelwal V, Wood GC et al (2006) Breast cancer in elderly women: outcome as affected by age, tumor features, comorbidities, and treatment approach. Clin Breast Cancer 7(1):59–66PubMedCrossRefPubMedCentralGoogle Scholar
  219. 219.
    Levy B (2009) Stereotype embodiment: a psychosocial approach to aging. Curr Dir Psychol Sci 18(6):332–336PubMedPubMedCentralCrossRefGoogle Scholar
  220. 220.
    Tsilimparis N, Perez S, Dayama A, Ricotta JJ 2nd. (2012) Age-stratified results from 20,095 aortoiliac aneurysm repairs: should we approach octogenarians and nonagenarians differently? J Am Coll Surg 215(5):690–701PubMedCrossRefPubMedCentralGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Department of Surgery, Sinai Center for Geriatric SurgerySinai HospitalBaltimoreUSA

Section editors and affiliations

  • Mark R. Katlic
    • 1
  1. 1.Department of Surgery, Center for Geriatric SurgerySinai Hospital and Northwest HospitalBaltimoreUSA

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