Botulinum Toxin for Hyperhidrosis in the Axillary Area

  • Ada Regina Trindade de AlmeidaEmail author
  • Suelen Montagner
Living reference work entry

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Part of the Clinical Approaches and Procedures in Cosmetic Dermatology book series (CAPCD)


Axillary hyperhidrosis (AH) impacts social and occupational lives of lots of people in all continents, and its real incidence probably is underestimated. Botulinum toxin is a safe and effective treatment option for axillary hyperhidrosis. Although its pathophysiology is not very clear, with some controversial topics, so far the beneficial effect of neuromodulators in inhibiting localized sweating temporarily is well known.

Before the procedure, the correct identification of the affected area is mandatory. The objective is to enhance efficacy avoiding drug waste or leaving areas without treatment, because the hyperhidrotic location does not always match the hairy axillary region.

Handling this medication, including dilution and injection techniques, depends on medical experience and may have some variations, including methods to make the procedure as painless as possible. Evidence supports a Level A recommendation for BoNT-A for axillary hyperhidrosis.


Axillary hyperhidrosis Excessive underarm sweating Botox Botulinum toxin Neuromodulators 


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© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Ada Regina Trindade de Almeida
    • 1
    Email author
  • Suelen Montagner
    • 2
  1. 1.Department of DermatologyHospital do Servidor Público Municipal de São Paulo (SP)São PauloBrazil
  2. 2.University of São PauloCampinasBrazil

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