Poly-l-Lactic Acid for Facial Treatment

  • Maria Helena Lesqueves SandovalEmail author
Living reference work entry

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Part of the Clinical Approaches and Procedures in Cosmetic Dermatology book series (CAPCD)


Aging is a complex process that takes place through interdependent changes in the tissues of the face. These changes are gradual and can be seen in the skin, muscle, fat compartments, and bone structures that lead to the overall appearance of facial aging (Fitzgerald and Vleggaar 2011).


Poly-l-lactic acid Biostimulators Facial aging Cosmetic techniques Cosmetic Injectable agents Injectable PLLA 


Since its approval for cosmetic use, injectable poly-l-lactic acid (PLLA) has become increasingly the choice for restoring a youthful appearance to the aging face. This minimally invasive procedure involves the creation of long-lasting volume in the region where it is reinjected without treating the wrinkle itself. However, due to the side effects which can ensue from the improper application of the product, it is essential that physicians follow consensus recommendations to obtain optimal patient results. The present article provides an overview of the history and instructions for injecting PLLA and specifically focuses on its use for facial volumization. Based on the large body of medical evidence available and 11 years’ clinical experience, the author also provides details for preparing, injecting, and reinjecting the product, using retrograde linear threading and depot injection techniques as well as a treatment plan with effective results avoiding complications and side effects.


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© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Cassiano Antonio Moraes University Hospital (HUCAM)VitoriaBrazil

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