Dermis consists mostly of protein fibers and extracellular matrix. Hyaluronic acid (HA) is an abundant glycosaminoglycan, natural compound of dermal extracellular matrix, with high affinity to water. This characteristic is determinant of skin viscoelasticity, hydration, structure, and firmness.
During aging process, collagenesis and elastogenesis are diminished, there are disorganization and degradation of dermic fibers and, finally, it is observed reduced glycosaminoglycans. These phenomena result in reduction of elasticity, density, and resistance of the skin.
Skin booster is a new concept of treatment which promotes a global improvement of the skin, by HA injections in dermis. The objective of this approach is to maintain skin hydration, delaying or reversing aging process, reducing aging indicators associated with loss of mechanical properties, and using small quantities of HA. It can be indicated to young or elderly people, preventing or treating senescence signs.
It is known that, after injected in dermis, HA improve hydration and stimulate collagen production, by mechanical tension, consequent to stretched fibers.
In this chapter, some aspects of physiological behavior of HA and how it takes part in aging process and skin booster treatment will be discussed.
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