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Non-Front-Fanged Colubroid Snakes

  • Scott A. WeinsteinEmail author
Reference work entry

Abstract

Non-front-fanged colubroid snakes (NFFC; formerly and artificially taxonomically assembled as “colubrids”) comprise the majority of extant ophidian species. Although the medical risks of bites by a handful of species have been documented, the majority of these snakes have oral products (Duvernoy’s secretions, or venoms) with unknown biomedical properties and their potential for causing harm in humans is unknown. Several genera of NFFC (the African boomslang, Dispholidus typus; the African twig, bird or vine snakes, Thelotornis spp.; the Japanese tiger keelback or Yamakagashi, Rhabdophis tigrinus; the red-necked keelback, R. subminiatus, and the rare Sri Lankan endemic, the blossom krait, Balanophis ceylonenesis) have inflicted life-threatening or fatal bites (termed, Hazard Level 1), while envenoming by several other NFFC species (e.g. Lichtenstein’s green racer, Philodryas olfersii; the Montpellier snake, Malpolon monspessulanus, and, possibly, the brown tree snake, Boiga irregularis) have caused uncommon systemic envenoming that were not life-threatening (Hazard Level 2). Several other NFFC taxa occasionally inflict bites that cause mild-moderate local envenoming that may resemble that caused by a crotaline viperid species (Hazard Level 2/3). The majority of documented bites from NFFC have either caused only mild local effects with limited medical significance, and bites from some taxa only occasionally cause more locally progressive effects (Hazard Level 3), while most are medically insignificant (Hazard Level 4). However, only a relative handful of bites or envenoming by NFFC taxa have been formally medically reviewed and documented, and thus the medical risks of the majority of NFFC species remain unestablished. Antivenom is available for serious envenoming by D. typus and R. tigrinus; the latter antivenom is probably also effective for treatment of envenoming by R. subminiatus and possibly B. ceylonensis. Medical management of most other species consists of supportive treatment, meticulous wound care and pain management. The controversial use of replacement therapy is discussed, and recommendations are detailed for management of each Hazard Level group. Future qualified documentation of NFFC bites and envenoming may facilitate improved risk assessments of a greater array of NFFC species.

Keywords

Colubrid Elapidae Colubroidea Front-fanged colubroids Vipers Cobras Mambas Coral snakes Sea snakes Naja Bungarus Kraits Bothrops Fer-de-lance Duvernoy’s gland Boomslangs Hazard index Coagulopathy Thrombocytopenia Hemolysis Metalloproteases Antivenom Neostigmine Atropine Garter snakes Cottonmouth Water moccasin Racers Cryoprecipitate Platelets Fibrinogen Fresh frozen plasma 

Notes

Acknowledgments

I gratefully acknowledge the generous contribution of images by Prof. David A. Warrell (Nuffield Department of Clinical Medicine, Oxford University), Prof. Idraneil Das (Institute of Biodiversity and Environmental Conservation, UNIMAS, Kota Samarahan, Sarawak), Prof. Julian White (Department of Toxinology, Women’s and Children’s Hospital, Adelaide), Dr. Dan Keyler (SafetyCall International and the Department of Experimental and Clinical Pharmacology, University of Minnesota), Dr. Ahmad Khalil Ismail (Department of Emergency Medicine, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur), Dr. Mohd Shukruddeen Salleh (Emergency and Trauma Department, Hospital Kuala Krai, Kuala Krai, Kelantan), Dr. Taksa Vasaruchapong (Thai Red Cross, Bangkok), Dr. Pedro H. Bernardo (Department of Ecology and Evolutionary Biology, University of Toronto, and the Department of Natural History, Royal Ontario Museum), Dr. Fábio Bucaretchi (Departamento de Pediatria, Faculdade de Ciências Médicas, Universidade Estadual de Campinas (UNICAMP), Campinas, and Centro de Controle de Intoxicações, Faculdade de Ciências Médicas, Hospital das Clínicas, UNICAMP), Dr. Eng Wah Teo (Department of Emergency Medicine, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur), Dr. Gordon Rodda (US Geographical Survey, Washington, DC, and Fort Collins Science Center, Fort Collins), Rowland Griffin (Project Chicchan, c/o Las Guacamayas Biological Station, Laguna del Tigre National Park, Flores, Guatemala), Dr. Barney Oldfield (Minneapolis), David P. Richards (School of Life Sciences, University of Nottingham), and Christopher E. Smith (Department of Fisheries, Wildlife, and Conservation Biology, University of Minnesota).

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Authors and Affiliations

  1. 1.Clinical and Research Toxinologist/Family PhysicianWomen’s and Children’s HospitalAdelaideAustralia

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